{"id":"W2305178018","doi":"10.4049/jimmunol.1501542","title":"ACKR4 on Stromal Cells Scavenges CCL19 To Enable CCR7-Dependent Trafficking of APCs from Inflamed Skin to Lymph Nodes","year":2016,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":70,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Beatson Institute for Cancer Research; University of Glasgow; Biotechnology and Biological Sciences Research Council; Cancer Research Institute; Medical Research Council; Cancer Research UK","keywords":"CCL19; CCL21; Lymph node stromal cell; Chemokine; Stromal cell; C-C chemokine receptor type 7; Dendritic cell; Lymphatic system; Inflammation; Antigen-presenting cell; High endothelial venules; Cell biology; Immunology; Lymph; Pathology; Chemokine receptor; Chemistry; T cell; Medicine; Biology; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001175709,0.0003279281,0.0007706483,0.0004438675,0.0002003531,0.00001579886,0.001204146,0.0003341477,0.0007535367],"category_scores_gemma":[0.0003935105,0.0001858583,0.0002398768,0.0002005505,0.0003410672,0.0001454792,0.0002091847,0.0004225943,0.0005948733],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001512481,"about_ca_system_score_gemma":0.0002163126,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001674339,"about_ca_topic_score_gemma":0.000009614437,"domain_scores_codex":[0.9968297,0.001226053,0.0009821551,0.0002238721,0.0001255031,0.0006126951],"domain_scores_gemma":[0.9967608,0.001604206,0.0006760645,0.0006649975,0.0002472092,0.0000467059],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01174778,0.00025181,0.0001269184,0.000006183457,0.0009883044,0.00001034082,0.002748116,0.0001015667,0.9487616,0.00008369949,0.0008059798,0.03436764],"study_design_scores_gemma":[0.003788441,0.0020541,0.008752263,0.0003663271,0.00009540517,0.0002150449,0.001305902,2.267952e-7,0.9653581,0.0001190895,0.01771823,0.0002269157],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9877756,0.00633141,0.0005525979,0.003074092,0.001779028,0.0002418248,0.00005711132,0.00002382217,0.0001645268],"genre_scores_gemma":[0.995755,0.001541553,0.0001537348,0.0005990034,0.00009568923,0.000006989977,0.000002981237,0.0000398343,0.001805247],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03414072,"threshold_uncertainty_score":0.8250698,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0105485268723325,"score_gpt":0.2293973501501925,"score_spread":0.21884882327786,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}