{"id":"W2305178018","doi":"10.4049/jimmunol.1501542","title":"ACKR4 on Stromal Cells Scavenges CCL19 To Enable CCR7-Dependent Trafficking of APCs from Inflamed Skin to Lymph Nodes","year":2016,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":70,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Beatson Institute for Cancer Research; University of Glasgow; Biotechnology and Biological Sciences Research Council; Cancer Research Institute; Medical Research Council; Cancer Research UK","keywords":"CCL19; CCL21; Lymph node stromal cell; Chemokine; Stromal cell; C-C chemokine receptor type 7; Dendritic cell; Lymphatic system; Inflammation; Antigen-presenting cell; High endothelial venules; Cell biology; Immunology; Lymph; Pathology; Chemokine receptor; Chemistry; T cell; Medicine; Biology; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000140664,0.0004102673,0.0002228315,0.0001809924,0.0001777112,0.0003405795,0.0002614537,0.0002773619,0.002964866],"category_scores_gemma":[0.0001095238,0.0001430681,0.000335535,0.0001179474,0.0001657806,0.0002420558,0.0003032592,0.0005293813,0.001206726],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002557595,"about_ca_system_score_gemma":0.0001916536,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000637238,"about_ca_topic_score_gemma":0.0007393112,"domain_scores_codex":[0.9996029,0.00006497718,0.00003157351,0.00006832774,0.00008332883,0.0001489492],"domain_scores_gemma":[0.9998713,0.00001434188,0.00003058113,0.00003068566,0.00002502654,0.00002804554],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002280063,0.000007699929,0.0001020888,0.00001424606,0.000001506638,0.00002716163,0.000005926445,0.00002602756,0.9991861,0.00004759066,0.00002608701,0.0005327518],"study_design_scores_gemma":[0.000005382787,0.00009209566,0.001441457,0.000003431615,0.000009015443,0.0001470726,0.00001964064,0.0007895222,0.9949962,0.00001777753,0.002475577,0.000002869131],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9893203,0.001226415,0.005997798,0.0001452407,0.00006232088,0.00003599245,0.0002985457,0.0001320244,0.002781394],"genre_scores_gemma":[0.9879512,0.0007670692,0.004993129,0.000128099,0.00003537389,0.00004047357,0.00071727,0.0000468932,0.005320481],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002964866,"threshold_uncertainty_score":0.009918451,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0105485268723325,"score_gpt":0.2293973501501925,"score_spread":0.21884882327786,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}