{"id":"W2305265714","doi":"10.4049/jimmunol.1501650","title":"Signal Inhibitory Receptor on Leukocytes-1 Limits the Formation of Neutrophil Extracellular Traps, but Preserves Intracellular Bacterial Killing","year":2016,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Neutrophil, Myeloperoxidase and Oxidative Mechanisms","field":"Immunology and Microbiology","cited_by":59,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Dutch Arthritis Association; Aard- en Levenswetenschappen, Nederlandse Organisatie voor Wetenschappelijk Onderzoek","keywords":"Neutrophil extracellular traps; Intracellular; Extracellular; NADPH oxidase; Opsonin; Receptor; Cell biology; Biology; Microbiology; Staphylococcus aureus; Inflammation; Reactive oxygen species; Immunology; Chemistry; Bacteria; Phagocytosis; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002410484,0.0003575413,0.0002964702,0.0001505568,0.0000849296,0.0004359689,0.0002406518,0.0002804651,0.001150707],"category_scores_gemma":[0.0002648222,0.00008094317,0.0001729613,0.00007134175,0.0002367023,0.0002307671,0.0001523485,0.0006537047,0.0003382607],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001860437,"about_ca_system_score_gemma":0.0003692319,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002362682,"about_ca_topic_score_gemma":0.0004032691,"domain_scores_codex":[0.9998197,0.00003696296,0.00001550341,0.00002020102,0.00005223431,0.00005546502],"domain_scores_gemma":[0.9998643,0.00002622726,0.00004565134,0.00001413422,0.00001764739,0.00003201773],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004925439,0.00009713666,0.0003437502,0.00005792368,0.000009878963,0.00004944911,0.00001108986,0.0001041128,0.9929674,0.0002520961,0.0001383991,0.005476269],"study_design_scores_gemma":[0.00007735293,0.001836564,0.004719081,0.00001534994,0.00004283412,0.0004126625,0.00003866859,0.00138847,0.9875295,0.0001213343,0.003813301,0.000004883627],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.989268,0.004584029,0.002785991,0.0003268539,0.00007204527,0.00003219542,0.0001683665,0.00008853999,0.002673961],"genre_scores_gemma":[0.9946499,0.001485447,0.001678801,0.0001411481,0.00002918088,0.00002317694,0.0002488799,0.000008650254,0.001734653],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001150707,"threshold_uncertainty_score":0.003849447,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01884175387668781,"score_gpt":0.2128494609895779,"score_spread":0.19400770711289,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}