{"id":"W2305876893","doi":"10.1093/annonc/mdw062","title":"Long-course oxaliplatin-based preoperative chemoradiation versus 5 × 5 Gy and consolidation chemotherapy for cT4 or fixed cT3 rectal cancer: results of a randomized phase III study","year":2016,"lang":"en","type":"article","venue":"Annals of Oncology","topic":"Colorectal Cancer Surgical Treatments","field":"Medicine","cited_by":444,"is_retracted":false,"has_abstract":false,"ca_institutions":"Juravinski Hospital","funders":"","keywords":"Medicine; Oxaliplatin; Colorectal cancer; Bolus (digestion); Randomized controlled trial; Urology; Toxicity; Chemotherapy; Clinical endpoint; Radiation therapy; Surgery; Cumulative incidence; Nuclear medicine; Gastroenterology; Internal medicine; Cancer; Cohort","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008178533,0.0001765609,0.00122267,0.0001000756,0.00003921287,0.000004012378,0.00005372248,0.0001271697,0.0001616478],"category_scores_gemma":[0.00126161,0.0001079132,0.0001470114,0.0001621222,0.0002628954,0.00007417061,0.00001411038,0.00005369674,8.103898e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001134621,"about_ca_system_score_gemma":0.0006515313,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002265885,"about_ca_topic_score_gemma":0.0004089123,"domain_scores_codex":[0.9983334,0.0002707786,0.0006825535,0.0003225128,0.0001911436,0.0001996418],"domain_scores_gemma":[0.9954572,0.003090402,0.0005936878,0.0001823507,0.000573982,0.00010237],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8814043,0.0027071,0.001524048,0.0000430054,0.000963133,0.00001443019,0.001146584,0.000006245388,0.002960186,0.00001304907,0.0004674544,0.1087504],"study_design_scores_gemma":[0.8783868,0.03437358,0.006072314,0.0001152217,0.000525156,0.000003913121,0.0001804862,0.0005450263,0.07922777,0.00002421122,0.0004207736,0.0001247441],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9895473,0.0002853526,0.0001511112,0.005227287,0.0002049945,0.003943133,0.0002044434,0.00002113033,0.0004152514],"genre_scores_gemma":[0.9978777,0.000434798,0.0003104549,0.0001995074,0.00009609164,0.0007645439,0.00005320845,0.00001735118,0.0002463438],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1086257,"threshold_uncertainty_score":0.4400572,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09973923631022293,"score_gpt":0.4517231968530698,"score_spread":0.3519839605428469,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}