{"id":"W2306161944","doi":"10.1152/ajpgi.00440.2015","title":"Butyrate enhances antibacterial effects while suppressing other features of alternative activation in IL-4-induced macrophages","year":2016,"lang":"en","type":"article","venue":"American Journal of Physiology-Gastrointestinal and Liver Physiology","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":66,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"Butyrate; Proinflammatory cytokine; Chemistry; Phagocytosis; Cell biology; Short-chain fatty acid; Macrophage; FOXP3; Biology; Biochemistry; Immunology; Immune system; Inflammation; Fermentation; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002350778,0.000534254,0.0003998844,0.0002013441,0.0001328124,0.0002228889,0.0002071502,0.000348825,0.00137677],"category_scores_gemma":[0.0001391243,0.0001325583,0.0003821465,0.0001134468,0.0002091432,0.0002253482,0.000272986,0.0007294532,0.0005032447],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001202912,"about_ca_system_score_gemma":0.0001997013,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002050284,"about_ca_topic_score_gemma":0.0004127425,"domain_scores_codex":[0.9997743,0.00006246029,0.00003861588,0.00002091699,0.00004168386,0.00006198759],"domain_scores_gemma":[0.9998612,0.00002079953,0.00003740258,0.00002053961,0.00002052395,0.00003950507],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004982237,0.00007446104,0.0001028838,0.0000394857,0.00000304585,0.00002699206,0.00001001251,0.00002031468,0.9983451,0.00001645023,0.00001268433,0.0008502842],"study_design_scores_gemma":[0.00009584756,0.0023455,0.004354201,0.00001246423,0.00002654863,0.0001801581,0.00003161311,0.0003369079,0.9908382,0.0000468871,0.001727257,0.000004482589],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951237,0.001986382,0.001482053,0.0001420093,0.00006276584,0.00004174652,0.0001738208,0.00004050659,0.0009470551],"genre_scores_gemma":[0.9926381,0.001459173,0.002558501,0.0001459593,0.00005348296,0.0001027495,0.0003778932,0.00001905776,0.002645023],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00137677,"threshold_uncertainty_score":0.00460577,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006935876082840291,"score_gpt":0.2451961739884286,"score_spread":0.2382602979055883,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}