{"id":"W2306872371","doi":"10.4049/jimmunol.184.supp.132.20","title":"Agonist CD40 antibody mediated stimulation of antigen presenting cells cannot replace CD4+ T help for an effective CD8+ killer response (132.20)","year":2010,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Saskatoon Medical Imaging; Saskatchewan Cancer Agency; University of Saskatchewan","funders":"","keywords":"Cytotoxic T cell; CTL*; CD8; MHC class I; Immunology; CD40; MHC class II; Biology; MHC restriction; Antigen; Major histocompatibility complex; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002190102,0.0005897572,0.0003854147,0.0001803238,0.0001073267,0.0003581873,0.0002925149,0.0004553928,0.004018763],"category_scores_gemma":[0.0001341394,0.0001980395,0.0002451637,0.00009697854,0.0002572344,0.0002956029,0.0002817441,0.0017151,0.001062792],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001965564,"about_ca_system_score_gemma":0.0002154299,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002483823,"about_ca_topic_score_gemma":0.0003614855,"domain_scores_codex":[0.9996892,0.0000506942,0.00003277252,0.0000542283,0.00007301169,0.0001000311],"domain_scores_gemma":[0.9997023,0.00005811646,0.00006850882,0.000036235,0.00002731762,0.0001075467],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001972267,0.00005245082,0.00006917898,0.00004583585,0.000003044322,0.00002972583,0.000007286073,0.00001778866,0.9990774,0.00007375584,0.00004018247,0.0003860778],"study_design_scores_gemma":[0.00004964742,0.0008553769,0.001561778,0.00001475873,0.00001530597,0.0002018773,0.00001843246,0.0005048756,0.9942909,0.00004931197,0.002434337,0.000003312804],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934389,0.001104479,0.001761241,0.0001440972,0.0001134953,0.00005086333,0.0004624014,0.0001042661,0.002820288],"genre_scores_gemma":[0.9845477,0.0007854136,0.003355634,0.0002188246,0.00005583922,0.0001171834,0.001252576,0.00006447971,0.009602453],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004018763,"threshold_uncertainty_score":0.01344407,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01072984659162757,"score_gpt":0.2821402905914813,"score_spread":0.2714104439998537,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}