{"id":"W2306974599","doi":"10.1093/cercor/bhw075","title":"eEF2K/eEF2 Pathway Controls the Excitation/Inhibition Balance and Susceptibility to Epileptic Seizures","year":2016,"lang":"en","type":"article","venue":"Cerebral Cortex","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":69,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Biotechnology and Biological Sciences Research Council; Istituto Italiano di Tecnologia; Israel Science Foundation; Ministry of Health, British Columbia; Ministry of Science and Technology; Wellcome Trust; National Institute of Mental Health; Wellcome; Fondazione Cariplo; Israel Society for Neuroscience; ERA-Net NEURON","keywords":"Neuroscience; Epilepsy; GABAergic; Neurotransmission; Inhibitory postsynaptic potential; Biology; Excitatory postsynaptic potential; Receptor; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007659772,0.0002736489,0.0002292266,0.0002222489,0.0001242571,0.0002546027,0.00009523929,0.0001987358,0.0006450422],"category_scores_gemma":[0.0001190236,0.0001010246,0.0001384429,0.00008636703,0.0001921685,0.0001551764,0.0001800984,0.0002671731,0.0001732105],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002429304,"about_ca_system_score_gemma":0.000139551,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005340888,"about_ca_topic_score_gemma":0.0006890577,"domain_scores_codex":[0.9999428,0.000009040066,0.000004088488,0.00001300717,0.000007642884,0.00002351905],"domain_scores_gemma":[0.999939,0.000005476546,0.00002096459,0.000006070684,0.000006051978,0.00002238223],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006072799,0.00003675919,0.001763049,0.00001865848,0.00001461753,0.000140391,0.00001658319,0.0001475509,0.9948304,0.0002019443,0.00008892437,0.002133854],"study_design_scores_gemma":[0.0001074241,0.0003860949,0.1495347,0.00001932191,0.0001070581,0.001729156,0.0001783407,0.006054782,0.8349499,0.0009093384,0.005990726,0.00003311365],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968036,0.0009195765,0.001372915,0.00006470655,0.00001193923,0.000005307093,0.0001498792,0.00004206341,0.0006299928],"genre_scores_gemma":[0.9985402,0.0003042192,0.0001993675,0.0000187319,0.000002557276,0.00000729285,0.000107894,0.000009872694,0.0008100714],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006450422,"threshold_uncertainty_score":0.002157867,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03623882881853303,"score_gpt":0.3077522698337876,"score_spread":0.2715134410152545,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}