{"id":"W2306974599","doi":"10.1093/cercor/bhw075","title":"eEF2K/eEF2 Pathway Controls the Excitation/Inhibition Balance and Susceptibility to Epileptic Seizures","year":2016,"lang":"en","type":"article","venue":"Cerebral Cortex","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":69,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Biotechnology and Biological Sciences Research Council; Istituto Italiano di Tecnologia; Israel Science Foundation; Ministry of Health, British Columbia; Ministry of Science and Technology; Wellcome Trust; National Institute of Mental Health; Wellcome; Fondazione Cariplo; Israel Society for Neuroscience; ERA-Net NEURON","keywords":"Neuroscience; Epilepsy; GABAergic; Neurotransmission; Inhibitory postsynaptic potential; Biology; Excitatory postsynaptic potential; Receptor; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004074652,0.0001731241,0.000177824,0.00008383019,0.0004543936,0.0001061369,0.0003376362,0.00005065368,0.0002400382],"category_scores_gemma":[0.00148101,0.00009570682,0.0000557373,0.0003849169,0.0006989247,0.0003603786,0.0001838736,0.0001990085,0.0003929494],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003644995,"about_ca_system_score_gemma":0.00007886904,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000057859,"about_ca_topic_score_gemma":0.00001469976,"domain_scores_codex":[0.9975635,0.0004847959,0.000243324,0.0007731624,0.0004041519,0.0005310882],"domain_scores_gemma":[0.9980934,0.001151178,0.00007400723,0.000381798,0.00007003349,0.000229544],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001006197,0.00004078133,0.003497873,0.000006859328,0.000001062977,0.00004688519,0.00008152656,6.747238e-7,0.9899609,0.001635504,0.001145277,0.003482036],"study_design_scores_gemma":[0.001587044,0.0007366439,0.1857526,0.00003150884,0.000009585638,0.0001243493,0.00004439031,0.0001982977,0.8026608,0.00485129,0.003708605,0.0002949152],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9898994,0.00001690027,0.0001410025,0.008068412,0.0003722735,0.0007255737,0.0000463289,0.00008725215,0.0006428618],"genre_scores_gemma":[0.9902261,0.0000446473,0.000008257721,0.00773181,0.0001190549,0.00008040151,3.321731e-7,0.00001664867,0.001772696],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1873001,"threshold_uncertainty_score":0.50507,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03623882881853303,"score_gpt":0.3077522698337876,"score_spread":0.2715134410152545,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}