{"id":"W2307118212","doi":"10.1093/neuonc/nov206.12","title":"ATCT-12RESULTS OF NRG ONCOLOGY/RTOG 9813- A PHASE III RANDOMIZED STUDY OF RADIATION THERAPY (RT) AND TEMOZOLOMIDE (TMZ) VERSUS RT AND NITROSOUREA (NU) THERAPY FOR ANAPLASTIC ASTROCYTOMA (AA)","year":2015,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier de l’Université de Montréal; University of Toronto; Université de Montréal; University of Calgary","funders":"","keywords":"Temozolomide; Nitrosourea; Anaplastic astrocytoma; Medicine; Radiation therapy; Oncology; Internal medicine; Astrocytoma; O-6-methylguanine-DNA methyltransferase; Glioma; Chemotherapy; Cancer research; Biology; Methyltransferase","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007770499,0.0003270324,0.001823603,0.0002820533,0.00007897103,0.00001146113,0.00009964454,0.00024429,0.00001554514],"category_scores_gemma":[0.0008137514,0.0002430618,0.0001604536,0.0001961033,0.0003005208,0.00007578707,0.0000465086,0.000181435,0.000001643212],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001844916,"about_ca_system_score_gemma":0.0003968229,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009584734,"about_ca_topic_score_gemma":0.0001698408,"domain_scores_codex":[0.9974635,0.0005960399,0.0008185406,0.0005057593,0.0002760828,0.0003400628],"domain_scores_gemma":[0.9945263,0.003958518,0.0006447536,0.0003166581,0.0002741079,0.0002796437],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8140088,0.008721037,0.004533063,0.00002690033,0.001070468,0.0001597893,0.003622452,0.0000187514,0.05082304,0.00003919055,0.001756286,0.1152202],"study_design_scores_gemma":[0.8523679,0.1116446,0.002339254,0.00001737354,0.0006520239,0.00008814607,0.001164209,0.0005228407,0.02291506,0.00004885499,0.008089789,0.000149972],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9916027,0.001686241,0.0000356791,0.0010582,0.0004834449,0.004785614,0.00005118789,0.00003616362,0.0002607975],"genre_scores_gemma":[0.9971745,0.001333016,0.0002640465,0.000292936,0.0001601746,0.0006799899,0.00005059404,0.00003761121,0.000007103596],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1150702,"threshold_uncertainty_score":0.9911771,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05169218472061766,"score_gpt":0.363098703875457,"score_spread":0.3114065191548393,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}