{"id":"W2307118212","doi":"10.1093/neuonc/nov206.12","title":"ATCT-12RESULTS OF NRG ONCOLOGY/RTOG 9813- A PHASE III RANDOMIZED STUDY OF RADIATION THERAPY (RT) AND TEMOZOLOMIDE (TMZ) VERSUS RT AND NITROSOUREA (NU) THERAPY FOR ANAPLASTIC ASTROCYTOMA (AA)","year":2015,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier de l’Université de Montréal; University of Toronto; Université de Montréal; University of Calgary","funders":"","keywords":"Temozolomide; Nitrosourea; Anaplastic astrocytoma; Medicine; Radiation therapy; Oncology; Internal medicine; Astrocytoma; O-6-methylguanine-DNA methyltransferase; Glioma; Chemotherapy; Cancer research; Biology; Methyltransferase","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005078266,0.001627229,0.002539549,0.0005795369,0.0005023133,0.0008161262,0.000984106,0.001454692,0.01154149],"category_scores_gemma":[0.003559467,0.0006403313,0.001785878,0.0007980719,0.000832315,0.0004705724,0.0003614129,0.002699572,0.001536163],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001017948,"about_ca_system_score_gemma":0.002801862,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009733309,"about_ca_topic_score_gemma":0.002734373,"domain_scores_codex":[0.9976799,0.001814934,0.00008593329,0.0001382694,0.0001579497,0.0001230427],"domain_scores_gemma":[0.9976445,0.0006757716,0.0006710165,0.0001287052,0.0001586417,0.0007213237],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9726931,0.005441981,0.001277345,0.000497263,0.0007428604,0.00004338444,0.00003943682,0.0004276214,0.002435485,0.00009839823,0.00268048,0.0136225],"study_design_scores_gemma":[0.932142,0.06229003,0.002061557,0.00003582845,0.0005853072,0.00004649794,0.000008694629,0.0003961926,0.0004528549,0.00009785434,0.001874124,0.000009021881],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9530539,0.005421925,0.001359601,0.001885056,0.001008001,0.02424015,0.006185602,0.0001838202,0.006661927],"genre_scores_gemma":[0.9307324,0.003963802,0.007599303,0.002612538,0.001088024,0.03412191,0.005717055,0.0001323087,0.01403273],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01154149,"threshold_uncertainty_score":0.0386101,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05169218472061766,"score_gpt":0.363098703875457,"score_spread":0.3114065191548393,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}