{"id":"W2307755391","doi":"10.1038/nrrheum.2016.23","title":"DNA-damaging autoantibodies and cancer: the lupus butterfly theory","year":2016,"lang":"en","type":"review","venue":"Nature Reviews Rheumatology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":86,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary; Quest University Canada; McGill University","funders":"National Center for Advancing Translational Sciences; National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Cancer Institute","keywords":"Medicine; Autoantibody; Systemic lupus erythematosus; Cancer; Dermatology; Immunology; Pathology; Internal medicine; Disease; Antibody","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00103519,0.0007896959,0.001257687,0.001658778,0.0003250052,0.001479764,0.0008946066,0.002592682,0.002415669],"category_scores_gemma":[0.001342786,0.000243292,0.0003827512,0.001556427,0.001472409,0.001917056,0.001134829,0.002871434,0.001133626],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009984267,"about_ca_system_score_gemma":0.001224506,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001039175,"about_ca_topic_score_gemma":0.001915761,"domain_scores_codex":[0.9997181,0.00006544709,0.00003026204,0.00004230997,0.0001101775,0.00003373306],"domain_scores_gemma":[0.9993801,0.0003361687,0.00007277129,0.00001960751,0.0001209066,0.00007041239],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000129919,0.00006528504,0.0004309195,0.007191937,0.00009990672,0.0004731903,0.00008675884,0.0004173925,0.001333595,0.01788164,0.09480283,0.8770866],"study_design_scores_gemma":[0.00002715438,0.00004630928,0.0005725997,0.00230833,0.00006859725,0.001769573,0.00007529811,0.0001097817,0.0002527125,0.01130789,0.9834448,0.00001704538],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00004506015,0.9980459,0.00008489859,0.0009143764,0.0004190318,8.942926e-7,0.000004329392,0.000002492292,0.0004829457],"genre_scores_gemma":[0.0009811448,0.995936,0.00008952466,0.0008847062,0.001488582,0.000002633136,0.000009826871,9.269563e-7,0.0006065921],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002592682,"threshold_uncertainty_score":0.008081198,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01793450241645841,"score_gpt":0.3187469524066699,"score_spread":0.3008124499902116,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}