{"id":"W2307792848","doi":"10.7554/elife.10288","title":"An extensive program of periodic alternative splicing linked to cell cycle progression","year":2016,"lang":"en","type":"article","venue":"eLife","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":172,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Institute of General Medical Sciences; National Cancer Institute; Canadian Institutes of Health Research; National Institutes of Health; University of Toronto","keywords":"Cell cycle; Alternative splicing; Biology; Mitosis; Cell biology; RNA splicing; Translation (biology); Restriction point; Gene; Cell growth; Genetics; Cell cycle progression; Computational biology; Messenger RNA; RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001138345,0.0001469739,0.0001844876,0.0004595036,0.0001858532,0.0003290435,0.0001137568,0.0001468751,0.0008537145],"category_scores_gemma":[0.0002079495,0.0001135659,0.0001644681,0.0003934669,0.0002765979,0.0001957286,0.0002240544,0.0002059699,0.0003029214],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000255128,"about_ca_system_score_gemma":0.0002124694,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005118442,"about_ca_topic_score_gemma":0.0008469659,"domain_scores_codex":[0.9998678,0.000009521129,0.000007540702,0.00006390145,0.00003218994,0.00001903107],"domain_scores_gemma":[0.9997414,0.00003741072,0.0001125045,0.00003153157,0.00004315008,0.00003404589],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001257826,0.00001124442,0.008355015,0.00005612201,0.00001156048,0.0001902772,0.00004789473,0.0001675914,0.9806168,0.0005249961,0.0001215653,0.009771127],"study_design_scores_gemma":[0.00003045127,0.0004118684,0.5636932,0.00003921234,0.00005864801,0.003008727,0.000169705,0.002383135,0.4176294,0.002749532,0.009786543,0.00003955571],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9923989,0.001665517,0.003221104,0.00006724088,0.00001222598,0.00001104109,0.0005412733,0.0001188891,0.001963836],"genre_scores_gemma":[0.9943557,0.0006843004,0.001709235,0.00006744502,0.00001799755,0.00001818046,0.000956499,0.00003067763,0.002159968],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008537145,"threshold_uncertainty_score":0.002855957,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01172248304038197,"score_gpt":0.3325935182185947,"score_spread":0.3208710351782127,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}