{"id":"W2307934198","doi":"10.1681/asn.2015091048","title":"Nephrin Tyrosine Phosphorylation Is Required to Stabilize and Restore Podocyte Foot Process Architecture","year":2016,"lang":"en","type":"article","venue":"Journal of the American Society of Nephrology","topic":"Renal Diseases and Glomerulopathies","field":"Medicine","cited_by":83,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; University of Guelph; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; University of Guelph","keywords":"Nephrin; Podocyte; Slit diaphragm; Tyrosine phosphorylation; Phosphorylation; Cell biology; Tyrosine; Biology; Actin cytoskeleton; Protein tyrosine phosphatase; Proto-oncogene tyrosine-protein kinase Src; Endocrinology; Internal medicine; Cytoskeleton; Biochemistry; Medicine; Kidney; Cell; Proteinuria","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001022391,0.0003098167,0.000253511,0.0001776323,0.0001855066,0.000277555,0.0002658123,0.0003215717,0.001136642],"category_scores_gemma":[0.0001491995,0.000170826,0.0002959582,0.0001245127,0.0002231434,0.0001771884,0.0002706195,0.000677805,0.0003786152],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004063484,"about_ca_system_score_gemma":0.000382753,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001320262,"about_ca_topic_score_gemma":0.001904882,"domain_scores_codex":[0.9997979,0.00001769951,0.00002675004,0.00004232764,0.00005046181,0.00006498428],"domain_scores_gemma":[0.9997703,0.0000185175,0.00007889728,0.00002490372,0.00001731977,0.0000900294],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000122952,0.00003836674,0.0001671762,0.00001789428,0.000005298356,0.00007762715,0.00001039836,0.00007050878,0.9986079,0.000101009,0.00004254741,0.0007382788],"study_design_scores_gemma":[0.00003564691,0.0001960221,0.01025884,0.000006126671,0.00001578153,0.0002531654,0.00003301822,0.001730506,0.9856313,0.00007189251,0.001759217,0.000008524653],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961793,0.000453948,0.001967555,0.00007515791,0.00003188885,0.00002878577,0.0004317162,0.0001269356,0.0007045765],"genre_scores_gemma":[0.9964706,0.000231433,0.001086841,0.00003335804,0.000005629169,0.00003609162,0.0004449064,0.00003117295,0.001660052],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001320262,"threshold_uncertainty_score":0.003802419,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01431112567096611,"score_gpt":0.2850698069259436,"score_spread":0.2707586812549775,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}