{"id":"W2308528637","doi":"10.1101/pdb.prot087817","title":"Generation and Validation of MYTH Baits: iMYTH and tMYTH Variants","year":2016,"lang":"en","type":"article","venue":"Cold Spring Harbor Protocols","topic":"Fungal and yeast genetics research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Yeast; Plasmid; Cytoplasm; Gene; Amino acid; Biology; Two-hybrid screening; Genetics; Saccharomyces cerevisiae","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000231906,0.00008885916,0.00009454089,0.00003634247,0.00004840873,0.00002926684,0.00007558369,0.00006951203,0.000009488494],"category_scores_gemma":[0.00008993338,0.0000669289,0.00001797705,0.00004340063,0.00006501719,0.000006933928,0.0001157153,0.00003235369,0.00000252166],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007156206,"about_ca_system_score_gemma":0.00005478826,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006047051,"about_ca_topic_score_gemma":0.000001781308,"domain_scores_codex":[0.9992781,0.00004865826,0.0001516774,0.000255255,0.0001208307,0.0001454382],"domain_scores_gemma":[0.9995554,0.000009782591,0.00005954947,0.0002042738,0.00009727288,0.0000737258],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004669892,0.00002406403,0.005724337,0.00005097699,0.00001392875,6.011013e-7,0.000005954066,0.000002098981,0.9919845,0.0006520945,0.00009575971,0.001398987],"study_design_scores_gemma":[0.0006936982,0.0002818728,0.01297687,0.00006283249,0.000004099638,8.530657e-7,0.000001451318,0.00008400238,0.9768686,0.00001660926,0.0089117,0.00009735473],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9865385,0.0001771489,0.003190369,0.0001784294,0.00002382546,0.009763901,0.00001809608,0.000007893236,0.0001018854],"genre_scores_gemma":[0.9927341,0.00008826182,0.001238282,0.00004355773,0.0001450234,0.005537701,0.000001461576,0.0000153639,0.0001962227],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01511584,"threshold_uncertainty_score":0.2729281,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0322706465387522,"score_gpt":0.2999948267491186,"score_spread":0.2677241802103664,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}