{"id":"W2308800788","doi":"10.1517/14728222.2016.1164695","title":"Calreticulin, a therapeutic target?","year":2016,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"Endoplasmic Reticulum Stress and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":64,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Calreticulin; Immunogenic cell death; Unfolded protein response; Endoplasmic reticulum; Cell biology; Biology; Programmed cell death; Extracellular; Cell; Intracellular; Apoptosis; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003975074,0.0004054275,0.0006661917,0.0003491111,0.0001630424,0.0008234532,0.0005275558,0.001981146,0.01051337],"category_scores_gemma":[0.0005350579,0.0000842529,0.0003385531,0.0002976305,0.0003792501,0.0009406184,0.0004611155,0.001950655,0.00484824],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006221843,"about_ca_system_score_gemma":0.0005120021,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003614994,"about_ca_topic_score_gemma":0.0009587279,"domain_scores_codex":[0.999814,0.00003566639,0.00001126593,0.00003826788,0.00006915798,0.0000316497],"domain_scores_gemma":[0.9998252,0.00004070596,0.00003117471,0.00000473616,0.00006921782,0.00002888391],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003349776,0.00006720746,0.0001838756,0.009593398,0.000089123,0.0005021435,0.00006117681,0.0003514923,0.0108451,0.008532362,0.2986488,0.6707903],"study_design_scores_gemma":[0.0000658478,0.0001453949,0.0002996704,0.001502001,0.00004797611,0.0008724623,0.00004813519,0.0001607285,0.001557859,0.003893006,0.991394,0.00001284146],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001501251,0.9432276,0.001480138,0.03341569,0.009166453,0.00004958812,0.0003618197,0.0001158417,0.01068163],"genre_scores_gemma":[0.01553921,0.92617,0.001636177,0.02766638,0.009477482,0.00009022225,0.0007338158,0.00003044912,0.01865622],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01051337,"threshold_uncertainty_score":0.03517073,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03550761811961399,"score_gpt":0.3494242121773451,"score_spread":0.3139165940577311,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}