{"id":"W2308800788","doi":"10.1517/14728222.2016.1164695","title":"Calreticulin, a therapeutic target?","year":2016,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"Endoplasmic Reticulum Stress and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":64,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Calreticulin; Immunogenic cell death; Unfolded protein response; Endoplasmic reticulum; Cell biology; Biology; Programmed cell death; Extracellular; Cell; Intracellular; Apoptosis; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001838417,0.001029524,0.001296707,0.0001579677,0.0001920621,0.00007131404,0.0007408095,0.0007788694,0.0006403954],"category_scores_gemma":[0.00005912136,0.0006719934,0.001103972,0.0001419468,0.0002092674,0.000006636714,0.0001672213,0.0003160757,0.000558002],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008380258,"about_ca_system_score_gemma":0.0003831292,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004055574,"about_ca_topic_score_gemma":4.794842e-7,"domain_scores_codex":[0.9963446,0.0004318874,0.0007461245,0.001256455,0.0004392111,0.0007817329],"domain_scores_gemma":[0.9977217,0.0001046624,0.0004057294,0.00130963,0.00009402059,0.000364197],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009480677,0.000241597,0.000001814289,0.0005893958,0.0005603131,0.0000118084,0.0000434547,0.000001316417,0.0001635403,0.001022476,0.009137394,0.9881321],"study_design_scores_gemma":[0.0006425756,0.0004160685,0.000001612861,0.002385252,0.00004355342,0.00003470729,0.00001811196,0.000004616382,0.0004226604,0.0002244834,0.9948777,0.0009286712],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[5.420852e-7,0.9933997,0.001169309,0.0001962584,0.002073556,0.0009075491,0.0001937759,0.00007668272,0.001982565],"genre_scores_gemma":[0.0001357753,0.9937443,0.0001551085,0.00152206,0.001802369,0.000550159,0.0008466751,0.0002204135,0.001023122],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9872034,"threshold_uncertainty_score":0.9995731,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03550761811961399,"score_gpt":0.3494242121773451,"score_spread":0.3139165940577311,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}