{"id":"W2308972734","doi":"10.1182/blood.v124.21.81.81","title":"Effect of Age on Efficacy and Safety Outcomes in Patients (Pts) with Newly Diagnosed Multiple Myeloma (NDMM) Receiving Lenalidomide and Low-Dose Dexamethasone (Rd): The First Trial","year":2014,"lang":"en","type":"article","venue":"Blood","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Vancouver General Hospital; Royal Victoria Hospital","funders":"","keywords":"Medicine; Internal medicine; Lenalidomide; Clinical endpoint; Thalidomide; Interim analysis; Multiple myeloma; Melphalan; Adverse effect; Gastroenterology; Prednisone; Dexamethasone; Surgery; Randomized controlled trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001719808,0.0006186497,0.001414297,0.000196646,0.0002317494,0.0007567934,0.0004731448,0.0007976237,0.001968733],"category_scores_gemma":[0.001770914,0.00024048,0.001651346,0.0002370263,0.0003931427,0.0005865078,0.0003444852,0.00190218,0.0002235041],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006391935,"about_ca_system_score_gemma":0.0006282967,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003040768,"about_ca_topic_score_gemma":0.0008554567,"domain_scores_codex":[0.9995108,0.0002863543,0.00004426444,0.0000652469,0.00003918162,0.00005421164],"domain_scores_gemma":[0.9986356,0.000372449,0.0005148838,0.000083477,0.00004699752,0.0003465752],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.9474585,0.004327001,0.01111445,0.0005353413,0.001560821,0.00006013711,0.00005915752,0.0005568184,0.002519117,0.00007377588,0.0006576228,0.0310773],"study_design_scores_gemma":[0.619531,0.3215905,0.05029554,0.0001791325,0.003005949,0.0002542539,0.00005023328,0.0008792219,0.001616722,0.0003063537,0.002257813,0.00003335374],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9912189,0.006538043,0.0001229225,0.0003476571,0.0001403352,0.000319222,0.0003386638,0.0000154615,0.0009587213],"genre_scores_gemma":[0.9964215,0.001564545,0.0002454072,0.0003676929,0.0002139565,0.0003262948,0.0003192351,0.000003310987,0.0005381078],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001968733,"threshold_uncertainty_score":0.009095311,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01153512142437186,"score_gpt":0.2679598743722015,"score_spread":0.2564247529478297,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}