{"id":"W2309253503","doi":"10.1139/cjc-2015-0582","title":"Prodruggability of carbohydrates — oral FimH antagonists","year":2016,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"Transgenic Plants and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung","keywords":"Prodrug; Chemistry; Bioavailability; Bioconversion; Absorption (acoustics); Hydrolysis; Enzyme; Biochemistry; Pharmacology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001072559,0.00007147672,0.0001147569,0.00001469051,0.00002963109,0.000006434144,0.0001980334,0.00007922029,0.00008906446],"category_scores_gemma":[0.0000651817,0.00005096233,0.00007815281,0.00004064442,0.000140763,0.000003122141,0.000006154877,0.00004880393,0.000001049585],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000204325,"about_ca_system_score_gemma":0.0008260327,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001652768,"about_ca_topic_score_gemma":0.0008034002,"domain_scores_codex":[0.9994622,0.000009239417,0.0002248503,0.0001005248,0.00005813909,0.0001449932],"domain_scores_gemma":[0.9993133,0.000008087897,0.0001220593,0.0001759569,0.0001297963,0.0002508106],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001241004,0.00001093683,0.007137915,0.00001686391,0.00002697016,0.000004397889,0.00001426908,0.00000160242,0.9898242,0.000009752732,0.001636473,0.001304211],"study_design_scores_gemma":[0.0002627859,0.00002711396,0.003271616,0.00002576592,0.00001058268,0.00006862514,0.00001900416,3.500672e-7,0.9575872,0.00009191407,0.03856312,0.00007189151],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978644,0.0003699999,0.0001589602,0.0005377235,0.00004144199,0.00003278717,0.0001807049,0.000001058915,0.0008129671],"genre_scores_gemma":[0.9993207,0.00003698415,0.0001541168,0.0000270652,0.0001110936,0.000001552041,0.0000105245,0.000006829783,0.0003311509],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03692665,"threshold_uncertainty_score":0.2078184,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007077848931449931,"score_gpt":0.2155878716790767,"score_spread":0.2085100227476268,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}