{"id":"W2310193808","doi":"10.1101/026831","title":"Widespread shortening of 3’ untranslated regions and increased exon inclusion are evolutionarily conserved features of innate immune responses to infection","year":2015,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"Canada Research Chairs; Compute Canada; National Science Foundation","keywords":"Innate immune system; Exon; Untranslated region; Gene isoform; Immune system; Gene; Transcriptome; Psychological repression; microRNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002275166,0.0001564271,0.0002591973,0.0002818384,0.000217962,0.0002941997,0.00009773031,0.000224069,0.0007631272],"category_scores_gemma":[0.0002860326,0.0001322986,0.0001782642,0.0002378402,0.0003652855,0.0001479256,0.0002096157,0.0002913926,0.0002316758],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009057409,"about_ca_system_score_gemma":0.00009643399,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002495907,"about_ca_topic_score_gemma":0.0005121034,"domain_scores_codex":[0.9997935,0.00002654788,0.00001628268,0.00008838649,0.00004680354,0.00002845728],"domain_scores_gemma":[0.9997131,0.00005539023,0.0001307354,0.00003792261,0.00003451392,0.0000282215],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00008567529,0.000007677799,0.01104696,0.00002534294,0.00001183862,0.00009771156,0.00007625511,0.00005099344,0.9863951,0.00003886156,0.00001973821,0.002143701],"study_design_scores_gemma":[0.00000645856,0.0002545773,0.6802102,0.00001546753,0.00003585447,0.001579318,0.0002944075,0.0006205364,0.3143976,0.0003742044,0.002199114,0.00001221983],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973385,0.0006556661,0.001327637,0.00003029331,0.000004616023,0.000003590789,0.0002067771,0.00002012316,0.0004128171],"genre_scores_gemma":[0.9971596,0.0002665968,0.001638653,0.00003818784,0.000008072051,0.00001044982,0.0002725127,0.00000987457,0.0005959966],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007631272,"threshold_uncertainty_score":0.002552867,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0134765080999538,"score_gpt":0.2370010600248771,"score_spread":0.2235245519249233,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}