{"id":"W2310485470","doi":"10.1155/2004/292580","title":"Translocation of <i>Clostridium difficile</i> Toxin B across Polarized Caco‐2 Cell Monolayers Is Enhanced by Toxin A","year":2004,"lang":"en","type":"article","venue":"Canadian Journal of Infectious Diseases and Medical Microbiology","topic":"Clostridium difficile and Clostridium perfringens research","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Boniface Hospital; University of Manitoba","funders":"","keywords":"Clostridium difficile toxin A; Toxin; Clostridium difficile toxin B; Microbiology; Caco-2; Clostridium difficile; Chromosomal translocation; Tight junction; Pore-forming toxin; Diarrhea; Biology; Cytotoxicity; Cell; Chemistry; Antibiotics; In vitro; Biochemistry; Microbial toxins; Medicine; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000217041,0.0002754109,0.0003162888,0.0001560782,0.0002255914,0.0004376253,0.0001220403,0.0003485355,0.0009697982],"category_scores_gemma":[0.0001811896,0.000185168,0.0003386899,0.000259241,0.0001569657,0.0002726314,0.0001985108,0.0004838032,0.0005352162],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002742253,"about_ca_system_score_gemma":0.0002203692,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001638096,"about_ca_topic_score_gemma":0.00140034,"domain_scores_codex":[0.9996203,0.00009011493,0.00003233808,0.00005852303,0.0001069662,0.00009168928],"domain_scores_gemma":[0.9998251,0.00005071246,0.00003680329,0.00002074434,0.00003171226,0.00003498133],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008429545,0.00001863837,0.0001017999,0.00001961948,0.000002288012,0.00002878511,0.00001281864,0.00001446181,0.9995099,0.00001816921,0.00003209579,0.000157254],"study_design_scores_gemma":[0.00002558622,0.0008533246,0.02269088,0.00002412161,0.000020301,0.0005426946,0.0001807436,0.001786962,0.9707466,0.00003756535,0.003079445,0.00001179101],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944578,0.000975412,0.00195465,0.0001892949,0.00003580327,0.00001678381,0.0003006765,0.00004204226,0.002027529],"genre_scores_gemma":[0.9915879,0.001239478,0.003601603,0.0001765797,0.00001834158,0.00003380187,0.001100052,0.00002243091,0.002219787],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001638096,"threshold_uncertainty_score":0.003257155,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006115049750407761,"score_gpt":0.2508700605228809,"score_spread":0.2447550107724731,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}