{"id":"W2311691805","doi":"10.1242/bio.016295","title":"Genetic basis of hindlimb loss in a naturally occurring vertebrate model","year":2016,"lang":"en","type":"article","venue":"Biology Open","topic":"Congenital heart defects research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Snow Foundation; Snow Medical; Medical Research Council; National Health and Medical Research Council; Institute of Genetics; Fondation pour la Recherche Médicale; Macquarie University","keywords":"Biology; Hindlimb; Zebrafish; Anatomy; Vertebrate; Transcription factor; Nuclear localization sequence; Fish fin; Gene; Cell biology; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002162198,0.0001101778,0.0001822465,0.00006689452,0.00002531763,0.00000962106,0.0005768362,0.0001783852,0.0000486186],"category_scores_gemma":[0.0001319274,0.00007781335,0.00005176485,0.00008646191,0.0001405028,0.000006034632,0.0007695051,0.00006835719,0.00003021247],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001679618,"about_ca_system_score_gemma":0.0001791079,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007375023,"about_ca_topic_score_gemma":0.0005712655,"domain_scores_codex":[0.99899,0.0001069353,0.000202402,0.0003502328,0.00005585016,0.000294588],"domain_scores_gemma":[0.9994449,0.00002810553,0.00004150773,0.0003543076,0.00006996215,0.00006121904],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002091061,0.00004617207,0.1648174,0.00001311719,0.00003286448,0.000007270391,0.00001562414,0.00001654666,0.8177521,0.0001460317,0.0003189459,0.01662482],"study_design_scores_gemma":[0.005784831,0.001637156,0.1365209,0.0001593228,0.00002324363,0.00007137312,0.00002756588,0.003182663,0.8353879,0.002476483,0.01386405,0.0008645543],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973976,0.0005038392,0.000280277,0.0001719965,0.00004695864,0.0003157285,0.00004486461,0.000003692115,0.00123505],"genre_scores_gemma":[0.9979396,0.0001102211,0.0008334677,0.0001296678,0.00003049359,0.00003825011,0.00000965905,0.00001316698,0.00089547],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0282965,"threshold_uncertainty_score":0.3173136,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02423495443792618,"score_gpt":0.3284684574956719,"score_spread":0.3042335030577458,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}