{"id":"W2312058115","doi":"10.1097/hjh.0000000000000801","title":"Hu antigen R is required for NOX-1 but not NOX-4 regulation by inflammatory stimuli in vascular smooth muscle cells","year":2015,"lang":"en","type":"article","venue":"Journal of Hypertension","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Cancer Institute; Canadian Institutes of Health Research; British Heart Foundation","keywords":"NOx; NADPH oxidase; Vascular smooth muscle; Downregulation and upregulation; Messenger RNA; Cell biology; Molecular biology; Chemistry; Reactive oxygen species; Biology; Biochemistry; Endocrinology; Gene; Smooth muscle","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001478287,0.0002753791,0.0002723571,0.0001563157,0.0002466219,0.0002188733,0.0002341327,0.0001830321,0.002397739],"category_scores_gemma":[0.0002477057,0.0001428118,0.0003788058,0.0000850524,0.0002575326,0.0001431805,0.0002190374,0.0002856696,0.0008035149],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002445129,"about_ca_system_score_gemma":0.000191621,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004704805,"about_ca_topic_score_gemma":0.0005110262,"domain_scores_codex":[0.9997811,0.0000422002,0.0000156938,0.00004400318,0.00005053816,0.00006648547],"domain_scores_gemma":[0.9997444,0.00003677411,0.00009940455,0.0000343763,0.00002605751,0.00005903426],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001051728,0.00002208251,0.0002977339,0.00002829016,0.000003549123,0.00009367301,0.00001132764,0.00001595808,0.998947,0.00005746938,0.00003006794,0.0003876757],"study_design_scores_gemma":[0.00003445362,0.0003409048,0.03605844,0.00001466189,0.00003156674,0.0007413286,0.00006895828,0.001347991,0.9580725,0.00009362321,0.003186023,0.000009566968],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951774,0.001354082,0.002288144,0.00008495105,0.000042003,0.00001398617,0.0001754018,0.00009055041,0.0007735314],"genre_scores_gemma":[0.9956596,0.0003433818,0.001465894,0.00005852778,0.00002290543,0.00003347494,0.0006700734,0.00002815251,0.001717962],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002397739,"threshold_uncertainty_score":0.008021235,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07047162956278293,"score_gpt":0.3008558413223699,"score_spread":0.230384211759587,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}