{"id":"W2312098803","doi":"10.1074/jbc.m116.717363","title":"Human Cells Cultured under Physiological Oxygen Utilize Two Cap-binding Proteins to recruit Distinct mRNAs for Translation","year":2016,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"Ontario Ministry of Research and Innovation; Natural Sciences and Engineering Research Council of Canada","keywords":"Translation (biology); Cell biology; Messenger RNA; Chemistry; Biology; Molecular biology; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001199011,0.000325483,0.0001997893,0.0002006587,0.0002453648,0.0002946409,0.0001514493,0.0003137349,0.001601913],"category_scores_gemma":[0.0001634128,0.0001400462,0.000193503,0.000244139,0.0002468226,0.0001985954,0.0003615763,0.0002097227,0.001032974],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001690279,"about_ca_system_score_gemma":0.0001522624,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005691625,"about_ca_topic_score_gemma":0.0006645616,"domain_scores_codex":[0.9998093,0.00002087585,0.00001542517,0.00006617731,0.00005563911,0.00003259697],"domain_scores_gemma":[0.9999064,0.00001922986,0.00002525917,0.00001519459,0.0000185574,0.00001524254],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001474424,0.00002203636,0.0009271745,0.00006514659,0.000007179091,0.00008224933,0.00005649836,0.00004454626,0.994406,0.0001816324,0.0001662809,0.0038937],"study_design_scores_gemma":[0.00002003412,0.0004797213,0.03096951,0.00002239711,0.00003250687,0.000974638,0.00008680196,0.0005724663,0.9465062,0.0002434739,0.02007362,0.00001853173],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9517528,0.0113476,0.02241325,0.0003195853,0.0002477465,0.0001779333,0.002325556,0.0002976342,0.01111797],"genre_scores_gemma":[0.9694475,0.004733977,0.01432944,0.0002398227,0.0001036734,0.0001132746,0.005189357,0.00003848627,0.005804438],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001601913,"threshold_uncertainty_score":0.005358934,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07314138290021119,"score_gpt":0.3112621558199369,"score_spread":0.2381207729197257,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}