{"id":"W2312242410","doi":"10.1158/1538-7445.am2013-4940","title":"Abstract 4940: Prognostic significance of Fbw7 in human melanoma and its role in cell migration.","year":2013,"lang":"en","type":"article","venue":"Cancer Research","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Melanoma; Gene knockdown; Ubiquitin ligase; Cancer research; Tissue microarray; Cell migration; Cancer; MAPK/ERK pathway; Cell growth; Biology; Medicine; Cell; Ubiquitin; Cell culture; Internal medicine; Kinase; Cell biology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000182471,0.0001716231,0.0002055577,0.0006296134,0.0002168083,0.0001864185,0.0001368483,0.0002917261,0.002027184],"category_scores_gemma":[0.0003649529,0.0000801677,0.000131931,0.0004534646,0.000120239,0.0001031873,0.0001489244,0.0001900348,0.0005231859],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002173408,"about_ca_system_score_gemma":0.0001117594,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001081678,"about_ca_topic_score_gemma":0.001010985,"domain_scores_codex":[0.9999253,0.000009410423,0.000006743295,0.00001467185,0.00002021215,0.00002356341],"domain_scores_gemma":[0.9998372,0.00002003515,0.00004554964,0.000008705564,0.00003795735,0.00005067439],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002063083,0.00005239754,0.8904924,0.0001305843,0.00006245304,0.002315745,0.00005859594,0.0002154581,0.05863718,0.0001176841,0.002137316,0.04371707],"study_design_scores_gemma":[0.00001609011,0.0001932055,0.9780315,0.00001656589,0.00007246296,0.003183958,0.00005961266,0.0007651837,0.01383213,0.0001512777,0.003669979,0.000008094894],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9921187,0.004125561,0.0004135661,0.0001764437,0.00005291369,0.00001645224,0.0009818892,0.00003947655,0.002075075],"genre_scores_gemma":[0.9973729,0.0004151212,0.0002170373,0.00002213632,0.00002101535,0.000009156897,0.000895444,0.000004679629,0.001042527],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002027184,"threshold_uncertainty_score":0.006781578,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03850026839509161,"score_gpt":0.3321735292689539,"score_spread":0.2936732608738623,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}