{"id":"W2312291776","doi":"10.1021/ac301142c","title":"Post-Trapping Derivatization of Radical-Derived EPR-Silent Adducts: Application to Free Radical Detection by HPLC/UV in Chemical, Biochemical, and Biological Systems and Comparison with EPR Spectroscopy","year":2012,"lang":"en","type":"article","venue":"Analytical Chemistry","topic":"Electron Spin Resonance Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Chemistry; Electron paramagnetic resonance; Spin trapping; Radical; Adduct; Nitroxyl; Derivatization; Photochemistry; Mass spectrometry; Chromatography; Organic chemistry; Nuclear magnetic resonance","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001826245,0.000253653,0.0004055147,0.00003380924,0.00005481211,0.00002156693,0.0001443289,0.0003089519,0.00000603004],"category_scores_gemma":[0.0003398501,0.0002209757,0.00003948664,0.0002172284,0.0004677422,0.00001064127,0.0001320835,0.0002152345,9.888483e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006025135,"about_ca_system_score_gemma":0.00002784482,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004121523,"about_ca_topic_score_gemma":0.000003195466,"domain_scores_codex":[0.9983606,0.00003820591,0.0004276891,0.0005441878,0.0001984764,0.0004307773],"domain_scores_gemma":[0.9991664,0.0000485011,0.0001342453,0.0003187656,0.00009214269,0.0002399598],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002133309,0.0001785339,0.01676792,0.0001109323,0.00005624477,4.337225e-7,0.00003883624,0.000004475851,0.9818249,0.00002338451,0.0004342035,0.0003467679],"study_design_scores_gemma":[0.000678151,0.0002187737,0.0041191,0.00004601473,0.00003597506,0.0000235202,0.0001693057,0.0005804492,0.9928487,0.00001094818,0.001001834,0.000267236],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9849282,0.003884733,0.01040774,0.0002945141,0.00001164348,0.0003165121,0.00002347098,0.00001940055,0.0001138218],"genre_scores_gemma":[0.9980403,0.0003373678,0.001143932,0.00008700498,0.0001348512,0.00008466174,0.0001373145,0.00002065131,0.00001388296],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01311217,"threshold_uncertainty_score":0.9011127,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007996585103680945,"score_gpt":0.2522980792718009,"score_spread":0.24430149416812,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}