{"id":"W2312291776","doi":"10.1021/ac301142c","title":"Post-Trapping Derivatization of Radical-Derived EPR-Silent Adducts: Application to Free Radical Detection by HPLC/UV in Chemical, Biochemical, and Biological Systems and Comparison with EPR Spectroscopy","year":2012,"lang":"en","type":"article","venue":"Analytical Chemistry","topic":"Electron Spin Resonance Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Chemistry; Electron paramagnetic resonance; Spin trapping; Radical; Adduct; Nitroxyl; Derivatization; Photochemistry; Mass spectrometry; Chromatography; Organic chemistry; Nuclear magnetic resonance","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009125212,0.0008274966,0.0003763021,0.0004825456,0.0002608715,0.0004654,0.0005352818,0.0007334132,0.001037824],"category_scores_gemma":[0.0009191626,0.0003335146,0.0002936171,0.0003725921,0.0004349154,0.0006206172,0.0003491725,0.0009900267,0.0005578907],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003002125,"about_ca_system_score_gemma":0.0004271112,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004428572,"about_ca_topic_score_gemma":0.0007238145,"domain_scores_codex":[0.9995306,0.0001407025,0.00003234655,0.0001219276,0.0001195019,0.00005501736],"domain_scores_gemma":[0.9993298,0.0002369026,0.0001455757,0.00009726276,0.0001465859,0.00004398042],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002374861,0.0000209781,0.00008867589,0.00006223725,0.000005204221,0.00002493654,0.0000154784,0.0000398427,0.996529,0.00005870718,0.00001601995,0.003115059],"study_design_scores_gemma":[0.00000289847,0.0001454094,0.0008534032,0.0000043089,0.00001050115,0.0001355668,0.000009576705,0.0003324232,0.9975465,0.00003777372,0.0009157968,0.000005971764],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"methods","genre_scores_codex":[0.7262506,0.01438837,0.2539335,0.0004214583,0.0001616502,0.0003772106,0.0005852906,0.0008087377,0.003073207],"genre_scores_gemma":[0.7298006,0.01356427,0.2472714,0.0004109262,0.0001396877,0.0005636171,0.000969123,0.0002185203,0.007061821],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.001037824,"threshold_uncertainty_score":0.00482589,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007996585103680945,"score_gpt":0.2522980792718009,"score_spread":0.24430149416812,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}