{"id":"W2312331607","doi":"10.1021/ol503213z","title":"The Concise Synthesis of Unsymmetric Triarylacetonitriles via Pd-Catalyzed Sequential Arylation: A New Synthetic Approach to Tri- and Tetraarylmethanes","year":2014,"lang":"en","type":"article","venue":"Organic Letters","topic":"Catalytic Cross-Coupling Reactions","field":"Chemistry","cited_by":90,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"Japan Society for the Promotion of Science; Natural Sciences and Engineering Research Council of Canada","keywords":"Acetonitriles; Chemistry; Combinatorial chemistry; Aryl; Palladium; Catalysis; Coupling reaction; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002617465,0.0008493635,0.0003150375,0.0002721673,0.0002260829,0.0003333382,0.0004529357,0.0003076597,0.001176146],"category_scores_gemma":[0.0001467135,0.0002638217,0.000254855,0.0002625408,0.0002394235,0.0005311585,0.0004910424,0.0007534163,0.001108696],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002686075,"about_ca_system_score_gemma":0.0005127613,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003268549,"about_ca_topic_score_gemma":0.001212096,"domain_scores_codex":[0.9998178,0.00001794,0.00002625337,0.00004366838,0.0000561443,0.0000383044],"domain_scores_gemma":[0.9998894,0.000009596341,0.00003724239,0.00001632648,0.00002022076,0.00002724966],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005777692,0.00007115479,0.0001464157,0.0001874204,0.00002401008,0.0003475577,0.00005004566,0.0004741473,0.9798306,0.001477269,0.0002783186,0.01705522],"study_design_scores_gemma":[0.00001477278,0.0002236658,0.0002985112,0.000008066124,0.00001822582,0.0006167961,0.00001623909,0.0008704808,0.9888626,0.0002162252,0.008839827,0.00001454244],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6672173,0.01700449,0.2715907,0.0007973593,0.0005628215,0.0004830628,0.001487954,0.001693981,0.03916242],"genre_scores_gemma":[0.9019129,0.01042105,0.07925744,0.0001667341,0.00008207445,0.000196935,0.0009220273,0.0001226777,0.00691816],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001176146,"threshold_uncertainty_score":0.003934622,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01170032598822661,"score_gpt":0.2259437082868754,"score_spread":0.2142433822986488,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}