{"id":"W2312520979","doi":"10.1158/1538-7445.am10-535a","title":"Abstract 535A: The tyrosine kinase Src co-operates with the ERM family member ezrin to promote Met activation and ECM degradation in a breast epithelial cell model","year":2010,"lang":"en","type":"article","venue":"Cancer Research","topic":"HER2/EGFR in Cancer Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"Ezrin; Proto-oncogene tyrosine-protein kinase Src; Invadopodia; Filopodia; Phosphorylation; Src family kinase; Cortactin; Cell biology; Moesin; Cancer research; Chemistry; Tyrosine phosphorylation; Cell migration; Biology; Cell; Cancer cell; Cytoskeleton; Cancer; Actin; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002161053,0.0003903176,0.0004142079,0.0002412993,0.0002396014,0.0003515966,0.0003229934,0.0004555777,0.00246394],"category_scores_gemma":[0.00008483863,0.0001830525,0.0003544539,0.0002293223,0.0002023676,0.0002136894,0.0002389084,0.0007068066,0.001141583],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004994801,"about_ca_system_score_gemma":0.0002585597,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001186267,"about_ca_topic_score_gemma":0.00124682,"domain_scores_codex":[0.9996648,0.00004696043,0.000033089,0.00005332388,0.0001171257,0.00008471819],"domain_scores_gemma":[0.9999242,0.00001007351,0.00001580708,0.00001542265,0.000009400805,0.00002501463],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001723029,0.00007333791,0.00008888853,0.00002564848,0.000006012942,0.0001021974,0.00000752894,0.0000695265,0.9985044,0.0001914335,0.0001823636,0.0005763389],"study_design_scores_gemma":[0.00005363786,0.0004352503,0.002375442,0.000005084628,0.00002175411,0.0004513415,0.00002691895,0.002983689,0.9891856,0.00006125835,0.004395239,0.000004914561],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9911249,0.001303633,0.002384444,0.0003863648,0.0001070385,0.00004728452,0.0009201694,0.0001000096,0.003626215],"genre_scores_gemma":[0.991356,0.0005214185,0.001810661,0.00007159943,0.00001557709,0.00005216421,0.0008453746,0.00002089285,0.005306214],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00246394,"threshold_uncertainty_score":0.008242667,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0869883775831335,"score_gpt":0.4163157521679209,"score_spread":0.3293273745847874,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}