{"id":"W2312601304","doi":"10.1152/physrev.00009.2014","title":"NOD-Like Receptors: Versatile Cytosolic Sentinels","year":2014,"lang":"en","type":"review","venue":"Physiological Reviews","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":352,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Biology; Receptor; Pattern recognition receptor; Cell biology; Innate immune system; Nod; Effector; Immune receptor; Acquired immune system; Rhodopsin-like receptors; Immune system; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.001042368,0.0008038327,0.004466586,0.0001453107,0.0002074298,0.00002974425,0.000751559,0.001092518,0.003802609],"category_scores_gemma":[0.0008808464,0.0004826321,0.001709892,0.0003402323,0.0002233175,0.00009754641,0.0002928076,0.0009704528,0.04961055],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000861099,"about_ca_system_score_gemma":0.00009236675,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006133009,"about_ca_topic_score_gemma":3.233094e-7,"domain_scores_codex":[0.9936122,0.003229688,0.001667559,0.0007711292,0.00005636557,0.0006630259],"domain_scores_gemma":[0.9972545,0.0005392177,0.001149862,0.0009532774,0.00005648245,0.00004667184],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000017502,0.00006478772,1.137285e-7,0.004967065,0.0001552773,0.00000129923,0.00002189032,5.730626e-8,0.001392638,0.0001590168,0.2555439,0.7376764],"study_design_scores_gemma":[0.0002047045,0.0001533007,0.00000284371,0.006228965,0.0004546499,0.00002832773,0.000002884002,2.701885e-7,0.00006761617,0.00002992051,0.9922975,0.0005290285],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00002032988,0.9957,0.00003016771,0.00002244309,0.001982056,0.001475429,0.000009931609,0.0001371655,0.0006224844],"genre_scores_gemma":[0.00001266575,0.991899,0.00004839159,0.0002419515,0.0003090681,0.0004941385,0.001649979,0.00004848185,0.005296319],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.7371474,"threshold_uncertainty_score":0.9997625,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09017998726601302,"score_gpt":0.3489890138287138,"score_spread":0.2588090265627008,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}