{"id":"W2313026868","doi":"10.1093/neuonc/nou255.44","title":"ET-46 * ONCOLYTIC VIRAL THERAPY FOR MALIGNANT GLIOMAS USING MYXOMA VIRUS DELETED FOR ANTI-APOPTOTIC M11L GENE","year":2014,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Myxoma virus; Oncolytic virus; Biology; Apoptosis; Programmed cell death; Small interfering RNA; Virology; Virus; Cancer research; Gene silencing; Cell culture; Gene; Transfection; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001190203,0.0003150195,0.0003221345,0.0001675112,0.000125017,0.0003028486,0.0001735397,0.0004693497,0.001476594],"category_scores_gemma":[0.00007392586,0.0001209354,0.0002328584,0.0001508197,0.0001895476,0.0002784682,0.0001677722,0.0008145336,0.0005055876],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002999505,"about_ca_system_score_gemma":0.0002081382,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000386209,"about_ca_topic_score_gemma":0.0003914426,"domain_scores_codex":[0.9998759,0.00002406285,0.00001518184,0.00002066615,0.00003534192,0.00002881845],"domain_scores_gemma":[0.9999459,0.000009079104,0.00001481817,0.000008512378,0.000004619572,0.00001708827],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005292429,0.0001840249,0.0002296718,0.00006529537,0.00001533036,0.00009596928,0.00002478935,0.0004171157,0.9935054,0.0004924907,0.0001559638,0.004284818],"study_design_scores_gemma":[0.0001227199,0.001584321,0.00116418,0.000006513101,0.00001768376,0.0005275197,0.00001459119,0.00239432,0.9883095,0.00007726842,0.005773359,0.000007941753],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933811,0.001532547,0.00210215,0.0001480116,0.00007194577,0.00006658187,0.0003664322,0.00009566571,0.002235416],"genre_scores_gemma":[0.9916958,0.0006295913,0.002566528,0.0000523306,0.00001076979,0.00005090897,0.0006823821,0.00001720071,0.004294526],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001476594,"threshold_uncertainty_score":0.004939675,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0413328903918742,"score_gpt":0.3550147754217088,"score_spread":0.3136818850298346,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}