{"id":"W2313378852","doi":"10.1097/qai.0000000000000662","title":"Effect of Cumulating Exposure to Abacavir on the Risk of Cardiovascular Disease Events in Patients From the Swiss HIV Cohort Study","year":2015,"lang":"en","type":"article","venue":"JAIDS Journal of Acquired Immune Deficiency Syndromes","topic":"HIV-related health complications and treatments","field":"Medicine","cited_by":83,"is_retracted":false,"has_abstract":true,"ca_institutions":"Royal Victoria Hospital; Royal Victoria Regional Health Centre; McGill University Health Centre; Group for Research in Decision Analysis; McGill University","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; McGill University; Gilead Sciences; ViiV Healthcare; GlaxoSmithKline; Bristol-Myers Squibb; Pfizer; National Science Foundation","keywords":"Abacavir; Medicine; Hazard ratio; Proportional hazards model; Marginal structural model; Cohort; Confidence interval; Cohort study; Relative risk; Risk factor; Internal medicine; Human immunodeficiency virus (HIV); Immunology; Antiretroviral therapy; Viral load","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003231403,0.0005236971,0.0004461382,0.0006112867,0.0004435619,0.0008228206,0.0004817071,0.000603048,0.002407827],"category_scores_gemma":[0.009138288,0.0002620798,0.001826417,0.0006969908,0.0002301378,0.0003328165,0.0006157561,0.0008612732,0.0001710578],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006195994,"about_ca_system_score_gemma":0.00090078,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.02154583,"about_ca_topic_score_gemma":0.02117745,"domain_scores_codex":[0.998368,0.0008706257,0.00008411189,0.0002330782,0.0002449525,0.0001992388],"domain_scores_gemma":[0.9905586,0.003955798,0.002401957,0.001446607,0.0008035366,0.0008334416],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003285855,0.00008319141,0.9887285,0.00004700109,0.001203529,0.0001886946,0.0001369115,0.001091521,0.000319114,0.00009684734,0.0005903736,0.00422838],"study_design_scores_gemma":[0.0001277342,0.0005939708,0.9932632,0.00002667911,0.0007185717,0.0002258603,0.00009009346,0.004190233,0.0001448572,0.0001461781,0.0004527115,0.00001995191],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972029,0.000701701,0.0003044356,0.0001805275,0.00002293691,0.00001566902,0.001167154,0.00001396667,0.0003907382],"genre_scores_gemma":[0.9984581,0.0001634571,0.0001657863,0.00003521441,0.00002343071,0.00001302249,0.00100829,0.000003480108,0.0001290844],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02154583,"threshold_uncertainty_score":0.04284084,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01775575129841826,"score_gpt":0.2863980182006929,"score_spread":0.2686422669022747,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}