{"id":"W2313425325","doi":"10.1097/pai.0000000000000181","title":"Immunohistochemistry as a Surrogate for Molecular Testing","year":2015,"lang":"en","type":"review","venue":"Applied immunohistochemistry & molecular morphology","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Biology; Gene; Molecular diagnostics; Computational biology; Fusion gene; Immunohistochemistry; Fusion protein; Molecular pathology; Epigenetics; Genetics; Recombinant DNA; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002707231,0.001081833,0.001597638,0.004651764,0.0003142213,0.002114662,0.001561328,0.001811041,0.002636148],"category_scores_gemma":[0.003703727,0.0004346336,0.0005416666,0.002679208,0.00262354,0.002531665,0.000999208,0.003117675,0.002692603],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001354051,"about_ca_system_score_gemma":0.001103701,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009396556,"about_ca_topic_score_gemma":0.0009760113,"domain_scores_codex":[0.9984701,0.0004325202,0.000223499,0.0002365767,0.0005641412,0.00007306355],"domain_scores_gemma":[0.9968055,0.001845022,0.0003639473,0.0001722995,0.0006892692,0.0001238355],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007940622,0.00006291975,0.001318399,0.01117446,0.000125395,0.00115751,0.0001302082,0.0005870846,0.003674237,0.02652987,0.05448396,0.9006765],"study_design_scores_gemma":[0.000008792151,0.00004834263,0.001339389,0.003151279,0.0000662833,0.008783872,0.0001090758,0.0002029368,0.001322929,0.008799748,0.9761348,0.00003255901],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001499218,0.9949139,0.0009467558,0.0009786399,0.000620998,0.000007667072,0.00001783886,0.00002141506,0.002342804],"genre_scores_gemma":[0.004148242,0.990216,0.001521681,0.001077664,0.001375175,0.0000213861,0.00006534137,0.00001145604,0.001563123],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004651764,"threshold_uncertainty_score":0.01431733,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04097338320963227,"score_gpt":0.3619092392813828,"score_spread":0.3209358560717505,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}