{"id":"W2313440605","doi":"10.17952/24aps.2015.172","title":"Peptide Coupling Challenges to Aza-Pipecolyl Smac Mimetic","year":2015,"lang":"en","type":"article","venue":"","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Coupling (piping); Computer science; Peptide; Chemistry; Engineering; Biochemistry; Mechanical engineering","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00144004,0.0003698016,0.0003406516,0.000194737,0.0003443079,0.0004796282,0.0005905072,0.0007087336,0.00184965],"category_scores_gemma":[0.001271845,0.0003406287,0.0001864765,0.0002604706,0.0003131408,0.0006830563,0.0003995921,0.001570767,0.0011261],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005743732,"about_ca_system_score_gemma":0.0004486798,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003978348,"about_ca_topic_score_gemma":0.0007633028,"domain_scores_codex":[0.9994573,0.0001440101,0.00003694135,0.00008083976,0.0001785981,0.0001023136],"domain_scores_gemma":[0.9994355,0.0002384057,0.00009180241,0.00005493538,0.000108897,0.0000704079],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006046427,0.00002012903,0.00009910254,0.0001417006,0.000009069385,0.0002226335,0.00010012,0.0002775464,0.9924292,0.001231048,0.0003421311,0.005066847],"study_design_scores_gemma":[0.000009760593,0.0001597518,0.0002993058,0.00001637136,0.00001447156,0.0003725321,0.00008528393,0.001477969,0.9845966,0.0003889587,0.01257153,0.00000759468],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8464748,0.006187472,0.1335215,0.002953468,0.0002937131,0.000384206,0.000343953,0.000445152,0.009395695],"genre_scores_gemma":[0.9099434,0.008433178,0.06921285,0.001030428,0.0001394978,0.0003717495,0.001028151,0.0001823179,0.009658498],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00184965,"threshold_uncertainty_score":0.007615685,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03441552013304322,"score_gpt":0.2632220658022925,"score_spread":0.2288065456692493,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}