{"id":"W2313482121","doi":"10.1158/2326-6066.cir-13-0208","title":"Murine Splenic CD4+ T Cells, Induced by Innate Immune Cell Interactions and Secreted Factors, Develop Antileukemia Cytotoxicity","year":2014,"lang":"en","type":"article","venue":"Cancer Immunology Research","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Cytotoxic T cell; Interleukin 12; Immunology; Cancer immunotherapy; Immune system; Immunotherapy; Biology; CD8; Acquired immune system; CTL*; Interleukin 21; Natural killer T cell; Antigen-presenting cell; T cell; Cell biology; Cancer research; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.000883112,0.0003932452,0.000554532,0.0005726498,0.0009061167,0.00007146248,0.0005056157,0.0006189419,0.004288787],"category_scores_gemma":[0.0002944358,0.0003667792,0.0001044199,0.000701999,0.0006619432,0.0003411783,0.0004872562,0.002706242,0.0008721728],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005184127,"about_ca_system_score_gemma":0.0002869243,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002623159,"about_ca_topic_score_gemma":0.0001099825,"domain_scores_codex":[0.9962146,0.001252194,0.0006358986,0.0007474344,0.0001144923,0.001035412],"domain_scores_gemma":[0.9978024,0.0006309739,0.0002310903,0.0006398432,0.0006310222,0.00006463361],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005029733,0.0001425373,0.0006521013,0.00003433597,0.0002518852,0.000001262818,0.0005168337,0.0000012738,0.9775793,0.00009708209,0.01805105,0.002169346],"study_design_scores_gemma":[0.001720685,0.0003661388,0.008758237,0.00004931722,0.00002284904,0.0000226592,0.0005583082,0.00003541378,0.766185,0.00002475406,0.2219562,0.0003003938],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9839706,0.007450247,0.0001334418,0.0003687198,0.004687545,0.0004480074,0.00003444054,0.0001595866,0.002747385],"genre_scores_gemma":[0.9738432,0.002170803,0.00001737597,0.0001296598,0.00006333155,0.0001459778,0.0004401357,0.00005674164,0.02313281],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2113943,"threshold_uncertainty_score":0.9999058,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03560949819122649,"score_gpt":0.314459115087851,"score_spread":0.2788496168966245,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}