{"id":"W2313491747","doi":"10.1038/srep23076","title":"Intra-articular injection of synovial mesenchymal stem cells improves cartilage repair in a mouse injury model","year":2016,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":128,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Children's Hospital; Alberta Bone and Joint Health Institute; University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Canadian Institutes of Health Research; Alberta Innovates; Alberta Innovates - Health Solutions","keywords":"Mesenchymal stem cell; Chondrogenesis; Progenitor cell; Cartilage; Osteoarthritis; Synovial membrane; Stem cell; Medicine; Stem cell transplantation for articular cartilage repair; Population; Synovial fluid; Synovial joint; Immunology; Pathology; Cell biology; Arthritis; Biology; Adult stem cell; Anatomy; Endothelial stem cell; Articular cartilage; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004651929,0.001126295,0.00098548,0.001635862,0.0002309491,0.0005765345,0.0005555255,0.0008308581,0.00221489],"category_scores_gemma":[0.0002170983,0.0002928768,0.0006210444,0.000377738,0.0005201857,0.0005765183,0.0002651934,0.001733904,0.0006172392],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002298687,"about_ca_system_score_gemma":0.0003971779,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006558985,"about_ca_topic_score_gemma":0.001059138,"domain_scores_codex":[0.9995238,0.00006328094,0.00005977382,0.00009764385,0.0001646373,0.00009080306],"domain_scores_gemma":[0.9994919,0.00004503043,0.0001907924,0.00005321957,0.00005313994,0.0001658562],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004417853,0.0005362002,0.0001154508,0.0001018924,0.0000155852,0.00004744657,0.00002752985,0.00008830665,0.9952921,0.0000539627,0.0000673707,0.003212551],"study_design_scores_gemma":[0.0001193183,0.006868957,0.002375565,0.00004113283,0.0001057802,0.0001835054,0.00007196037,0.0007682972,0.9879006,0.00007349817,0.001478077,0.0000133065],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9872816,0.004759438,0.004439746,0.0003463386,0.0002247883,0.0001065055,0.0003756133,0.0005669818,0.001898868],"genre_scores_gemma":[0.981527,0.003965786,0.005883065,0.0001778835,0.00008658607,0.0001173283,0.0007239721,0.00008566958,0.00743269],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00221489,"threshold_uncertainty_score":0.007409513,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01050914520439531,"score_gpt":0.2336841909363746,"score_spread":0.2231750457319793,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}