{"id":"W2313491747","doi":"10.1038/srep23076","title":"Intra-articular injection of synovial mesenchymal stem cells improves cartilage repair in a mouse injury model","year":2016,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":128,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Children's Hospital; Alberta Bone and Joint Health Institute; University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Canadian Institutes of Health Research; Alberta Innovates; Alberta Innovates - Health Solutions","keywords":"Mesenchymal stem cell; Chondrogenesis; Progenitor cell; Cartilage; Osteoarthritis; Synovial membrane; Stem cell; Medicine; Stem cell transplantation for articular cartilage repair; Population; Synovial fluid; Synovial joint; Immunology; Pathology; Cell biology; Arthritis; Biology; Adult stem cell; Anatomy; Endothelial stem cell; Articular cartilage; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008603879,0.0001613926,0.0003306422,0.0002916453,0.00006796161,0.00002135691,0.00004460633,0.0001133399,0.00003245609],"category_scores_gemma":[0.00005387535,0.0001115422,0.0001773027,0.0003135134,0.0001715307,0.0002374001,0.0000508052,0.00007482107,0.00001458219],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001226025,"about_ca_system_score_gemma":0.000241159,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001983539,"about_ca_topic_score_gemma":0.0000529654,"domain_scores_codex":[0.9978341,0.00004042609,0.0006635444,0.0006379543,0.0004903963,0.0003335152],"domain_scores_gemma":[0.9986986,0.0000158381,0.0002379016,0.0007431139,0.0001560127,0.0001485676],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000118155,0.0002119337,0.001066137,0.00003987272,0.00001051525,0.000440113,0.0003554099,0.00001458754,0.9891905,0.00004917568,0.0008903309,0.007613281],"study_design_scores_gemma":[0.0007873397,0.0006971939,0.00003542535,0.0001513547,0.00005019677,0.0001848571,0.0001127146,0.0003382683,0.9964392,0.000773509,0.0003090003,0.0001209932],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966639,0.00009155094,0.0001977635,0.00006218436,0.002009688,0.0006590968,0.00001302643,0.0001124925,0.0001903312],"genre_scores_gemma":[0.9880846,0.000005520938,0.0005903077,0.00001648879,0.00004384076,0.00004386478,0.000006850472,0.00002003433,0.01118846],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01099813,"threshold_uncertainty_score":0.4548558,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01050914520439531,"score_gpt":0.2336841909363746,"score_spread":0.2231750457319793,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}