{"id":"W2313560996","doi":"10.1021/jo3012754","title":"A Stereoselective Approach to β-<scp>l</scp>-Arabino Nucleoside Analogues: Synthesis and Cyclization of Acyclic 1′,2′-<i>syn</i><i>N</i>,<i>O</i>-Acetals","year":2012,"lang":"en","type":"article","venue":"The Journal of Organic Chemistry","topic":"Carbohydrate Chemistry and Synthesis","field":"Chemistry","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Université de Montréal; Montreal Clinical Research Institute","funders":"","keywords":"Chemistry; Stereoselectivity; Acetal; Stereochemistry; Steric effects; Nucleophile; Nucleoside; Pyrimidine; Combinatorial chemistry; Organic chemistry; Catalysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001116085,0.0004779837,0.0001582393,0.000154739,0.0001475212,0.0001865327,0.0002325074,0.0001580254,0.00123458],"category_scores_gemma":[0.0001039566,0.000130976,0.0001524816,0.0001283398,0.0001518541,0.0002707431,0.0002390018,0.0004815694,0.0005107579],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001829965,"about_ca_system_score_gemma":0.0003443203,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003640085,"about_ca_topic_score_gemma":0.0009423286,"domain_scores_codex":[0.9999171,0.00001860603,0.000007126616,0.00002203305,0.00001618613,0.00001888943],"domain_scores_gemma":[0.9999406,0.000007341576,0.00002083108,0.000009543623,0.000008711938,0.00001293937],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005738366,0.00002425552,0.00007672222,0.00006462113,0.000004761014,0.0001551517,0.00004105603,0.000289186,0.991048,0.0006110966,0.00007597599,0.007551807],"study_design_scores_gemma":[0.000008387114,0.00024387,0.0003271424,0.00000435928,0.000006603241,0.0003431391,0.00001469821,0.0002527748,0.9925739,0.00008895727,0.006128298,0.000007832118],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.938616,0.003190843,0.03232242,0.0002303664,0.0001106415,0.0001969861,0.000621901,0.000255364,0.02445548],"genre_scores_gemma":[0.9722828,0.002470189,0.02026395,0.0001038204,0.0000306779,0.00007954163,0.0003974492,0.00004783276,0.004323756],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00123458,"threshold_uncertainty_score":0.004130125,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01293617991929396,"score_gpt":0.2123106896846623,"score_spread":0.1993745097653684,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}