{"id":"W2313791989","doi":"10.1097/icl.0b013e318281ae06","title":"Physical Entrapment of Hyaluronic Acid During Synthesis Results in Extended Release From Model Hydrogel and Silicone Hydrogel Contact Lens Materials","year":2013,"lang":"en","type":"article","venue":"Eye & Contact Lens Science & Clinical Practice","topic":"Ocular Surface and Contact Lens","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Hyaluronic acid; Self-healing hydrogels; Lysozyme; Silicone; Contact lens; Controlled release; Wetting; Chemistry; Contact angle; Sorption; Silicone hydrogel; Swelling; Chemical engineering; Adsorption; Polymer chemistry; Materials science; Biochemistry; Organic chemistry; Nanotechnology; Composite material","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002464579,0.0003161206,0.0001594684,0.0001188566,0.00008526134,0.0002424759,0.0001099981,0.0002171534,0.0007626844],"category_scores_gemma":[0.0002591669,0.0001195502,0.0002667992,0.000133002,0.0001716247,0.0003305855,0.0001386562,0.000220976,0.0001397148],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000243401,"about_ca_system_score_gemma":0.0001486898,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002142125,"about_ca_topic_score_gemma":0.0003925154,"domain_scores_codex":[0.9998254,0.00002603404,0.00001951824,0.00003914274,0.00006640724,0.0000234553],"domain_scores_gemma":[0.9998038,0.00006207199,0.00007659754,0.0000219387,0.00002002538,0.00001550566],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003568243,0.000008179656,0.00007724697,0.00003420685,0.000003120019,0.00001953921,0.000008540863,0.0000330877,0.9991003,0.00001067621,0.000002703837,0.0006666332],"study_design_scores_gemma":[0.000004172522,0.0002186515,0.0007931538,0.000002613197,0.000006185092,0.00005705198,0.000004961068,0.000157211,0.9984587,0.000004768215,0.0002907771,0.000001732279],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9921432,0.002069722,0.005062692,0.00002027334,0.00001423169,0.00002957164,0.00006975593,0.00002227378,0.0005683776],"genre_scores_gemma":[0.9929106,0.0008413913,0.004888754,0.00001702617,0.00000668086,0.00003440558,0.0001136775,0.00001370455,0.001173837],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007626844,"threshold_uncertainty_score":0.002551377,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03159403350467202,"score_gpt":0.3368239822046877,"score_spread":0.3052299487000157,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}