{"id":"W2313791989","doi":"10.1097/icl.0b013e318281ae06","title":"Physical Entrapment of Hyaluronic Acid During Synthesis Results in Extended Release From Model Hydrogel and Silicone Hydrogel Contact Lens Materials","year":2013,"lang":"en","type":"article","venue":"Eye & Contact Lens Science & Clinical Practice","topic":"Ocular Surface and Contact Lens","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Hyaluronic acid; Self-healing hydrogels; Lysozyme; Silicone; Contact lens; Controlled release; Wetting; Chemistry; Contact angle; Sorption; Silicone hydrogel; Swelling; Chemical engineering; Adsorption; Polymer chemistry; Materials science; Biochemistry; Organic chemistry; Nanotechnology; Composite material","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch","metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.003176848,0.0005188501,0.00152782,0.0002429488,0.0002270053,0.0001448581,0.0005087417,0.0002814782,0.0001209671],"category_scores_gemma":[0.01177769,0.0004528867,0.000294347,0.0004850492,0.0005923115,0.002709605,0.0003242905,0.0009207812,0.0002027013],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002811036,"about_ca_system_score_gemma":0.0008873591,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001829333,"about_ca_topic_score_gemma":0.00007571827,"domain_scores_codex":[0.9937136,0.0004084896,0.002017128,0.001537416,0.001272497,0.001050941],"domain_scores_gemma":[0.9934834,0.00311464,0.001010225,0.001358532,0.0004357962,0.0005974222],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003179235,0.002273964,0.01030949,0.00006494809,0.0001652558,0.0002068033,0.0007206858,0.00004831365,0.9800885,0.0006554495,0.00001244523,0.00227494],"study_design_scores_gemma":[0.0107359,0.002313508,0.3880989,0.00096815,0.000952791,0.00003635417,0.001386721,0.02475134,0.5689528,0.0005715077,0.0002599139,0.0009721572],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935617,0.0003529899,0.00003126177,0.003173879,0.0002391726,0.001212246,0.00009534199,0.00008211717,0.001251334],"genre_scores_gemma":[0.9965678,0.0008258274,0.001053593,0.001132604,0.0001842939,0.00007531235,0.00001350123,0.00005092796,0.00009611434],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4111357,"threshold_uncertainty_score":0.9997923,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03159403350467202,"score_gpt":0.3368239822046877,"score_spread":0.3052299487000157,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}