{"id":"W2314063606","doi":"10.1021/nn500790m","title":"A Proposed Mechanism of the Influence of Gold Nanoparticles on DNA Hybridization","year":2014,"lang":"en","type":"article","venue":"ACS Nano","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University","funders":"British Columbia Knowledge Development Fund","keywords":"Colloidal gold; DNA–DNA hybridization; DNA; Nanoparticle; Biosensor; Nanotechnology; Nucleic acid; Nucleic acid thermodynamics; Oligonucleotide; Base pair; Materials science; Biophysics; Chemistry; Biochemistry; Biology; Base sequence","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007540215,0.00110205,0.0006586208,0.0006974616,0.0007803694,0.0009347787,0.002328355,0.002299519,0.004221605],"category_scores_gemma":[0.001512243,0.0008067402,0.001096279,0.0002519639,0.001181681,0.001737903,0.0005670954,0.001607698,0.001350943],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008645942,"about_ca_system_score_gemma":0.0007860961,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007205256,"about_ca_topic_score_gemma":0.0005780047,"domain_scores_codex":[0.9994532,0.00007277205,0.00003201306,0.0002239344,0.0001320476,0.00008600407],"domain_scores_gemma":[0.999448,0.0003148021,0.00006400103,0.00003363206,0.00008411909,0.00005550529],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001945539,0.0002801672,0.001238126,0.001230922,0.000094851,0.001606043,0.0003407237,0.0049953,0.9354798,0.0394826,0.001173732,0.01388305],"study_design_scores_gemma":[0.0001011574,0.0006288979,0.0009783867,0.00004105265,0.0000800875,0.001357421,0.00008045656,0.05443684,0.9281866,0.008482924,0.005542214,0.0000839385],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5108356,0.009949265,0.4388038,0.009557443,0.003154618,0.001443901,0.0007476808,0.003224412,0.02228329],"genre_scores_gemma":[0.9161342,0.003367634,0.06537499,0.001061945,0.0001285703,0.0005861767,0.0002108416,0.00005207931,0.01308359],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004221605,"threshold_uncertainty_score":0.01412272,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004961182694361081,"score_gpt":0.2256132102631619,"score_spread":0.2206520275688009,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}