{"id":"W2314318485","doi":"10.1021/bc500280q","title":"Single-Walled Carbon Nanotubes Noncovalently Functionalized with Lipid Modified Polyethylenimine for siRNA Delivery <i>in Vitro</i> and <i>in Vivo</i>","year":2014,"lang":"en","type":"article","venue":"Bioconjugate Chemistry","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lawson Health Research Institute; Cancer Care Ontario; Western University","funders":"Canadian Institutes of Health Research; National Natural Science Foundation of China; Canadian Cancer Society; London Health Sciences Centre","keywords":"Chemistry; Polyethylenimine; In vivo; In vitro; Carbon nanotube; Nanotechnology; Biophysics; Gene delivery; Biochemistry; Transfection; Gene; Biotechnology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001935047,0.0003216592,0.0003349087,0.00004901158,0.00004698861,0.00003687805,0.0001857128,0.0002749357,0.00001557619],"category_scores_gemma":[0.00006463881,0.000300028,0.00009158764,0.00009268572,0.0001281476,0.000009198113,0.00008225949,0.0001143251,0.000001003721],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003826873,"about_ca_system_score_gemma":0.00007572406,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008435006,"about_ca_topic_score_gemma":0.00007306075,"domain_scores_codex":[0.9984013,0.00003570467,0.0003502276,0.0006687452,0.0001380423,0.000405912],"domain_scores_gemma":[0.9992837,0.0000513472,0.0001103987,0.0003402676,0.0001034818,0.0001107539],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003300429,0.0001333489,0.0005103489,0.0001260089,0.00004237561,0.000004129583,0.00002134776,0.00006947248,0.9946861,0.000002407416,0.000174296,0.000929687],"study_design_scores_gemma":[0.003937385,0.0003019941,0.00007911266,0.00007559436,0.00002679837,0.00002221852,0.00005910412,0.000686676,0.9824952,0.00002389554,0.01189537,0.0003965985],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958429,0.0009015572,0.0001378501,0.0001543955,0.00009528227,0.0003110094,0.0000581879,0.00001824528,0.002480513],"genre_scores_gemma":[0.9967593,0.0002582102,0.0003966461,0.0004017009,0.0003488491,0.000117086,0.0001672085,0.00004087972,0.001510131],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0121909,"threshold_uncertainty_score":0.9999452,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0110254109150317,"score_gpt":0.209869124361333,"score_spread":0.1988437134463013,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}