{"id":"W2314318485","doi":"10.1021/bc500280q","title":"Single-Walled Carbon Nanotubes Noncovalently Functionalized with Lipid Modified Polyethylenimine for siRNA Delivery <i>in Vitro</i> and <i>in Vivo</i>","year":2014,"lang":"en","type":"article","venue":"Bioconjugate Chemistry","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lawson Health Research Institute; Cancer Care Ontario; Western University","funders":"Canadian Institutes of Health Research; National Natural Science Foundation of China; Canadian Cancer Society; London Health Sciences Centre","keywords":"Chemistry; Polyethylenimine; In vivo; In vitro; Carbon nanotube; Nanotechnology; Biophysics; Gene delivery; Biochemistry; Transfection; Gene; Biotechnology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001298579,0.000357833,0.0001559767,0.0001709556,0.0001246754,0.0001549753,0.0002228095,0.0004079165,0.0005026404],"category_scores_gemma":[0.0001377267,0.0001627912,0.0002106678,0.0001359296,0.0001373824,0.0001984762,0.000109202,0.0002885663,0.0003657818],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000335985,"about_ca_system_score_gemma":0.000230738,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005931957,"about_ca_topic_score_gemma":0.001273399,"domain_scores_codex":[0.9998906,0.00001262124,0.00001062456,0.00002810075,0.00004419671,0.00001386974],"domain_scores_gemma":[0.9999281,0.00001208005,0.00002213022,0.00000790611,0.00001922465,0.00001054301],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000009810943,0.00000488608,0.0000253245,0.00001602947,0.000001830325,0.00001300033,0.000001894874,0.00005658605,0.9989849,0.00003630885,0.00001799232,0.000831545],"study_design_scores_gemma":[0.000002006157,0.00004462475,0.0002796094,0.000001583708,0.00000377194,0.0000383289,0.000001286383,0.0006990646,0.9979552,0.0000112735,0.0009609159,0.0000023639],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9527648,0.006055543,0.03542606,0.000194578,0.0001372426,0.0001595345,0.0002846682,0.0002757926,0.004701765],"genre_scores_gemma":[0.9489338,0.002996988,0.03755321,0.000167708,0.00002706277,0.0001538829,0.0006652433,0.00006201835,0.009440166],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005931957,"threshold_uncertainty_score":0.00243777,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0110254109150317,"score_gpt":0.209869124361333,"score_spread":0.1988437134463013,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}