{"id":"W2314348083","doi":"10.1021/nn5007418","title":"A Graphene-Based Biosensing Platform Based on the Release of DNA Probes and Rolling Circle Amplification","year":2014,"lang":"en","type":"article","venue":"ACS Nano","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":155,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Graphene; Aptamer; Biosensor; Primer (cosmetics); Nanotechnology; Rolling circle replication; Oxide; Materials science; Analyte; DNA; Molecule; Molecular recognition; Combinatorial chemistry; Biophysics; Chemistry; Polymerase; Biochemistry; Biology; Molecular biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002622889,0.0001049075,0.0001138263,0.00005930004,0.0001066559,0.00001692008,0.0000813414,0.00009163603,2.955412e-7],"category_scores_gemma":[0.0001372715,0.0000760251,0.00006316966,0.0001347413,0.0001173069,0.0000025872,0.00001851514,0.00004874233,4.491893e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005453484,"about_ca_system_score_gemma":0.00002232822,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008675129,"about_ca_topic_score_gemma":0.000009055711,"domain_scores_codex":[0.9993303,0.00004481277,0.0001609765,0.0002379875,0.0001032557,0.000122709],"domain_scores_gemma":[0.9993356,0.00005384932,0.000126089,0.0003742085,0.00007931173,0.00003087745],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006012246,0.00004140703,0.0002362899,0.0000117195,0.00001071031,1.625475e-7,0.000005049385,0.00006186335,0.9872434,0.00009236659,0.00004196161,0.01219494],"study_design_scores_gemma":[0.0002034298,0.0002228349,0.0003510313,0.00004699866,0.0000236059,9.484483e-7,0.00001785428,0.003182628,0.9947245,0.0002833799,0.000838325,0.0001044422],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9869544,0.0000410624,0.01227724,0.0003661384,0.00001359202,0.0001285077,0.000005555284,0.00002489783,0.0001886099],"genre_scores_gemma":[0.9960886,0.00002285249,0.003343547,0.0004360407,0.00003905771,0.000004344764,0.00004359875,0.00001224292,0.000009702307],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0120905,"threshold_uncertainty_score":0.3100213,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01088709415435879,"score_gpt":0.2344244052962798,"score_spread":0.223537311141921,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}