{"id":"W2314404171","doi":"10.1021/acscatal.5b00082","title":"Direct Macrolactonization of Seco Acids via Hafnium(IV) Catalysis","year":2015,"lang":"en","type":"article","venue":"ACS Catalysis","topic":"Chemical Synthesis and Reactions","field":"Chemistry","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Centre in Green Chemistry and Catalysis","funders":"","keywords":"Hafnium; Catalysis; Chemistry; Combinatorial chemistry; Enantioselective synthesis; Stereochemistry; Organic chemistry; Zirconium","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001566413,0.0001915741,0.0004098193,0.00009349624,0.0000730457,0.00002949738,0.0002829898,0.0001915963,0.0006199236],"category_scores_gemma":[0.0002674141,0.0001686149,0.0002495327,0.0005885514,0.00008583017,0.0001656051,0.0001068554,0.0001328096,0.0001207887],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001406642,"about_ca_system_score_gemma":0.00005091762,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008010947,"about_ca_topic_score_gemma":0.00009933527,"domain_scores_codex":[0.9986547,0.0000156357,0.0003952268,0.0003395539,0.0003606289,0.0002342383],"domain_scores_gemma":[0.9985897,0.0001098332,0.0002281578,0.0006824834,0.0001983547,0.0001914587],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002564647,0.0002448521,0.007450557,0.00005439079,0.0004173434,0.00000319948,0.0004065435,0.00006677725,0.980315,0.000009421979,0.001135446,0.009870877],"study_design_scores_gemma":[0.0002352077,0.000005956342,0.0002191205,0.0000149191,0.0004905987,0.000006808692,0.0001771612,0.0002708771,0.9868165,0.00005252369,0.01150455,0.0002058083],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9523545,0.0003857366,0.0004698632,0.0002064402,0.00007607972,0.00004398695,0.00007382264,0.0001242779,0.04626532],"genre_scores_gemma":[0.9959817,0.00004928904,0.0001637112,0.0000229699,0.0001366699,0.00001807067,0.0007722988,0.00003129355,0.002823987],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04362724,"threshold_uncertainty_score":0.6875916,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01325913897289781,"score_gpt":0.22645203864745,"score_spread":0.2131928996745522,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}