{"id":"W2314443567","doi":"10.1021/ol201005s","title":"Efficient and Controllably Selective Preparation of Esters Using Uronium-Based Coupling Agents","year":2011,"lang":"en","type":"article","venue":"Organic Letters","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":112,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"","keywords":"Chemistry; Reagent; Phenol; Selectivity; Alcohol; Primary (astronomy); Coupling (piping); Coupling reaction; Combinatorial chemistry; Base (topology); Tertiary alcohols; Organic chemistry; Catalysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004421323,0.0008155485,0.0004867894,0.0003524048,0.0002109362,0.0004251776,0.0004509264,0.0004145595,0.001617059],"category_scores_gemma":[0.0004822217,0.0004424449,0.0002969562,0.0003445353,0.0002337758,0.0006739239,0.000598919,0.0005983385,0.001431321],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000224965,"about_ca_system_score_gemma":0.0002937991,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002059306,"about_ca_topic_score_gemma":0.00039739,"domain_scores_codex":[0.9997347,0.00004938201,0.00003415982,0.00005830832,0.00005519505,0.00006823503],"domain_scores_gemma":[0.9997868,0.00003603184,0.00006435119,0.00003395998,0.00003423512,0.00004470333],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006326424,0.00001171348,0.00004254276,0.00009352158,0.000005552844,0.0001055635,0.00001868239,0.00007990603,0.9950178,0.0002211205,0.00006304795,0.004277314],"study_design_scores_gemma":[0.00000573754,0.00002994159,0.00006349034,0.000004254679,0.00000415459,0.00006449232,0.000003338886,0.0001048737,0.9979399,0.00002178883,0.001754459,0.000003488603],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8497515,0.009497279,0.1236218,0.0003586903,0.0003212027,0.0004793565,0.0006267421,0.000835126,0.01450825],"genre_scores_gemma":[0.9109978,0.008977759,0.06340504,0.0002581183,0.00008497832,0.0003141151,0.000606649,0.0003007369,0.01505488],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001617059,"threshold_uncertainty_score":0.005409539,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.011925492212328,"score_gpt":0.2317168107753109,"score_spread":0.219791318562983,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}