{"id":"W2314443567","doi":"10.1021/ol201005s","title":"Efficient and Controllably Selective Preparation of Esters Using Uronium-Based Coupling Agents","year":2011,"lang":"en","type":"article","venue":"Organic Letters","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":112,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"","keywords":"Chemistry; Reagent; Phenol; Selectivity; Alcohol; Primary (astronomy); Coupling (piping); Coupling reaction; Combinatorial chemistry; Base (topology); Tertiary alcohols; Organic chemistry; Catalysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007207596,0.00007659164,0.0001093829,0.00002129953,0.00003220123,0.000006550128,0.00004996839,0.00004487438,0.00002158633],"category_scores_gemma":[0.00002987876,0.00007062668,0.00004632938,0.00006502122,0.00004583652,0.00000112721,0.00002157803,0.00002565689,7.960026e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001804968,"about_ca_system_score_gemma":0.00002321939,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003051922,"about_ca_topic_score_gemma":0.000004917846,"domain_scores_codex":[0.9995053,0.00001398812,0.0001274846,0.0001826245,0.00006620218,0.0001043573],"domain_scores_gemma":[0.9997348,0.00000817686,0.00008374145,0.0001098292,0.00002988155,0.00003354548],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005805439,0.00003102512,0.002441729,0.000007493924,0.00005614047,4.925401e-7,0.00006292098,0.001174005,0.9960961,9.02436e-7,0.00003108356,0.00004001933],"study_design_scores_gemma":[0.0003615996,0.00003998515,0.0008253237,0.000008578966,0.00006956139,0.000001066365,0.00002132796,0.0181328,0.9804382,7.804487e-7,0.00002010457,0.00008070437],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993821,0.00008163119,0.005935172,0.00004911469,0.00001678262,0.00006572335,0.000002521071,0.000003874341,0.00002416179],"genre_scores_gemma":[0.9991604,0.000003937305,0.0004997614,0.0002902534,0.00002439638,0.000001683168,0.000006898677,0.000009935656,0.000002746975],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0169588,"threshold_uncertainty_score":0.2880073,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.011925492212328,"score_gpt":0.2317168107753109,"score_spread":0.219791318562983,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}