{"id":"W2314558962","doi":"10.4161/23723556.2014.975082","title":"Tumor suppression by stromal TIMPs","year":2016,"lang":"en","type":"article","venue":"Molecular & Cellular Oncology","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; Ontario Institute for Cancer Research","funders":"","keywords":"Stromal cell; Stroma; Cancer research; Microvesicles; Biology; Matrix metalloproteinase; Cancer-Associated Fibroblasts; Function (biology); RHOA; Cell biology; Tumor progression; Cancer; Tumor microenvironment; Gene; microRNA; Signal transduction; Genetics; Immunology; Tumor cells; Immunohistochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002019892,0.0003826387,0.0002248331,0.0002988241,0.0001330126,0.0004596699,0.000135064,0.0001595733,0.002151577],"category_scores_gemma":[0.0001638275,0.0000772239,0.0002410822,0.0001289387,0.0001910387,0.0001581173,0.000201998,0.0007491044,0.0005516296],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001695984,"about_ca_system_score_gemma":0.0002137375,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002529728,"about_ca_topic_score_gemma":0.0003212592,"domain_scores_codex":[0.9998596,0.00002823398,0.00001300438,0.00001924595,0.00004023748,0.00003963247],"domain_scores_gemma":[0.999856,0.00003165478,0.00003459653,0.00001937418,0.00001823624,0.00004015699],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001880567,0.00004006807,0.0002490149,0.00005390185,0.000007489603,0.0001274991,0.00001281115,0.00009951626,0.9914022,0.000378823,0.0002470311,0.007193654],"study_design_scores_gemma":[0.00003490522,0.0004105845,0.001744315,0.000006523364,0.00001847916,0.0007189044,0.00003073813,0.001129255,0.9850735,0.0002113277,0.01061754,0.000004017227],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9662187,0.01076945,0.01185224,0.001072312,0.0002983133,0.00006200575,0.0009644569,0.0006825913,0.008080035],"genre_scores_gemma":[0.9913686,0.002447722,0.001688854,0.00008225225,0.00004344578,0.00002602265,0.000354619,0.00003092598,0.003957502],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002151577,"threshold_uncertainty_score":0.007197738,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004745293321617768,"score_gpt":0.2285363619742436,"score_spread":0.2237910686526258,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}