{"id":"W2314657015","doi":"10.1158/1538-7445.am2011-sy02-02","title":"Abstract SY02-02: Interaction of MMPs with oncogenic signaling: Disruption of dynamic reciprocity and tissue polarity","year":2011,"lang":"en","type":"article","venue":"Cancer Research","topic":"S100 Proteins and Annexins","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier de l’Université de Montréal","funders":"","keywords":"MMP9; Cancer research; Cell biology; MAPK/ERK pathway; Cancer; Biology; Signal transduction; Downregulation and upregulation; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001477208,0.0005747662,0.0003561508,0.0003215288,0.0002793411,0.0006127846,0.0003572849,0.0003368463,0.01098491],"category_scores_gemma":[0.0001231854,0.0001688655,0.0002072608,0.0003178025,0.0002702201,0.0002407069,0.0002429638,0.0005906462,0.003209891],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004594204,"about_ca_system_score_gemma":0.0003775177,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007743059,"about_ca_topic_score_gemma":0.001312254,"domain_scores_codex":[0.9998282,0.00001984102,0.00001548598,0.00002338539,0.00007334744,0.00003971356],"domain_scores_gemma":[0.9999093,0.00001405058,0.00001686074,0.00001034108,0.0000123429,0.00003715933],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003565733,0.00009381158,0.0001289604,0.00005483077,0.000007370905,0.0001199968,0.000008524752,0.0001049469,0.9926972,0.000423433,0.002470151,0.003534295],"study_design_scores_gemma":[0.00009999463,0.0004887128,0.002099331,0.00000725734,0.00001451226,0.0003852466,0.0000246628,0.002087758,0.9789968,0.0001623188,0.0156236,0.000009843005],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"other","genre_scores_codex":[0.934841,0.005752756,0.00687565,0.001915346,0.001299762,0.0002374372,0.006446746,0.001270454,0.0413608],"genre_scores_gemma":[0.9200345,0.003095641,0.006223531,0.0003689601,0.000193944,0.0001307871,0.008861289,0.0002410889,0.06085027],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.01098491,"threshold_uncertainty_score":0.03674817,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07766793069941999,"score_gpt":0.3989079198622246,"score_spread":0.3212399891628046,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}