{"id":"W2314662733","doi":"10.1158/1538-7445.am10-5010","title":"Abstract 5010: Nucleophosmin (NPM) is univerally deregulated in acute promyelocytic leukemia","year":2010,"lang":"en","type":"article","venue":"Cancer Research","topic":"Retinoids in leukemia and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ontario Institute for Cancer Research","funders":"","keywords":"Nucleophosmin; Ribosome biogenesis; Biology; Acute promyelocytic leukemia; Cancer research; Cell biology; Cell culture; Molecular biology; Retinoic acid; Myeloid leukemia; Ribosome; Genetics; RNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007445328,0.0001886021,0.0001191162,0.0003188587,0.0001699892,0.0002426251,0.0001291784,0.0002663108,0.001938253],"category_scores_gemma":[0.0001064129,0.0001059165,0.00009508221,0.0002635286,0.0002826839,0.0001314701,0.0001896436,0.0002449632,0.0006582813],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002509142,"about_ca_system_score_gemma":0.00009750085,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003551404,"about_ca_topic_score_gemma":0.0003391341,"domain_scores_codex":[0.9998753,0.00001495383,0.0000135947,0.00003188736,0.00004351026,0.00002078555],"domain_scores_gemma":[0.9999102,0.00001000718,0.00003769497,0.0000074358,0.000006443525,0.0000282206],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001223692,0.00001024572,0.0008059133,0.00001813661,0.000003527846,0.0003503117,0.000008461418,0.00002378737,0.9973056,0.00007433046,0.00006671606,0.001210553],"study_design_scores_gemma":[0.00003055754,0.0003133748,0.06744119,0.000009132472,0.00002238744,0.007036061,0.0000891963,0.0008978788,0.91681,0.0002251092,0.007118939,0.000006077321],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"other","genre_scores_codex":[0.9958239,0.0009323306,0.001089411,0.0000757223,0.00001557992,0.00001141638,0.0005768472,0.00007942799,0.001395473],"genre_scores_gemma":[0.9968657,0.0002793353,0.0006472,0.00003185988,0.000006725503,0.00001181542,0.000501021,0.00001384207,0.001642437],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.001938253,"threshold_uncertainty_score":0.006484091,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02073165205111431,"score_gpt":0.3435020645604866,"score_spread":0.3227704125093723,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}