{"id":"W2314668519","doi":"10.1097/00007890-201211271-00928","title":"Increased Expression of the Inhibitory B-Cell Molecule CD22 on CD27+IgM+ B Cells Containing ABO-Antibody-Secreting Cells: A Role in Susceptibility to B-Cell Tolerance after ABO-Incompatible Infant Heart Transplantation?","year":2012,"lang":"en","type":"article","venue":"Transplantation","topic":"Transplantation: Methods and Outcomes","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"CD22; B cell; Antigen; ABO blood group system; CD19; Antibody; Immunology; Biology; Naive B cell; Immune system; Flow cytometry; Molecular biology; T cell; Antigen-presenting cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001179182,0.000160007,0.000119729,0.0003075562,0.0001050906,0.0002352809,0.0001365419,0.0001925203,0.001999621],"category_scores_gemma":[0.0001441371,0.00006673447,0.00009253065,0.0001109517,0.0001522842,0.0001542901,0.0001481957,0.0001891302,0.0003292738],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001296282,"about_ca_system_score_gemma":0.00007663899,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002787928,"about_ca_topic_score_gemma":0.0002189384,"domain_scores_codex":[0.9999412,0.00001107872,0.000005010416,0.00001193653,0.00001123453,0.00001954613],"domain_scores_gemma":[0.9999064,0.00001420153,0.00003349886,0.000006604311,0.00001297954,0.0000262606],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0003614611,0.0000540015,0.04667417,0.00005433299,0.00001430072,0.0006006614,0.00008572531,0.00004041106,0.9470559,0.00006131474,0.00005196241,0.004945679],"study_design_scores_gemma":[0.00002459114,0.001111519,0.6942556,0.00003109584,0.00009058296,0.006296039,0.0004099022,0.0005868978,0.2942978,0.0001114703,0.002774143,0.00001018456],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990218,0.0004805489,0.0001313304,0.00001144318,0.000001695597,0.000002801796,0.00003390614,0.000005237329,0.000311358],"genre_scores_gemma":[0.9990243,0.0003252489,0.0001124356,0.00001413659,0.000008170622,0.000005972518,0.0001034241,0.000002588009,0.0004035935],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001999621,"threshold_uncertainty_score":0.00668937,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01003603033880059,"score_gpt":0.2833158584289895,"score_spread":0.2732798280901889,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}