{"id":"W2314763031","doi":"10.1021/jp303138s","title":"Application of a Fluorescent <i>C</i>-Linked Phenolic Purine Adduct for Selective N7-Metalation of DNA","year":2012,"lang":"en","type":"article","venue":"The Journal of Physical Chemistry B","topic":"DNA and Nucleic Acid Chemistry","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Nucleobase; Chemistry; Circular dichroism; Pyrimidine; Adduct; Stereochemistry; Substrate (aquarium); Deoxyguanosine; DNA; Fluorescence; Nucleoside; Oligonucleotide; Organic chemistry; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001656487,0.0003753711,0.0001755814,0.00009339933,0.000137426,0.0001858501,0.0003402535,0.000473726,0.0006069524],"category_scores_gemma":[0.0001664758,0.000175933,0.000158192,0.0001147145,0.0001978723,0.0001682042,0.0002022264,0.0002787678,0.0002193536],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002903255,"about_ca_system_score_gemma":0.0001293018,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007075641,"about_ca_topic_score_gemma":0.0008904791,"domain_scores_codex":[0.9998465,0.00002295393,0.000006986655,0.00006225439,0.00003350583,0.00002778997],"domain_scores_gemma":[0.9998626,0.0000242086,0.00005188375,0.00001578184,0.00002307612,0.00002247896],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001801325,0.000004282399,0.00003374139,0.00001545031,0.000001684634,0.00001047144,0.000007476163,0.00002864169,0.9994501,0.00001954369,0.000006896257,0.0004037071],"study_design_scores_gemma":[0.000001450256,0.00005665991,0.0002293477,8.662879e-7,0.000002244078,0.00003090551,0.000002930173,0.0001625537,0.9991829,0.000003204714,0.0003254017,0.000001506846],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9893432,0.0004662906,0.008452911,0.00004899892,0.00001286008,0.00003087696,0.00009197852,0.0001226462,0.001430209],"genre_scores_gemma":[0.9905212,0.0003157216,0.007420691,0.00004564902,0.000005081268,0.00002734753,0.000142926,0.00001784512,0.00150364],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007075641,"threshold_uncertainty_score":0.002106428,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00647594969141956,"score_gpt":0.2460553359095075,"score_spread":0.2395793862180879,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}