{"id":"W2315058715","doi":"10.1021/acs.inorgchem.5b02109","title":"Induction of Cytotoxicity in Pyridine Analogues of the Anti-metastatic Ru(III) Complex NAMI-A by Ferrocene Functionalization","year":2015,"lang":"en","type":"article","venue":"Inorganic Chemistry","topic":"Ferrocene Chemistry and Applications","field":"Chemistry","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency; Simon Fraser University","funders":"Natural Sciences and Engineering Research Council of Canada; University of British Columbia; Simon Fraser University; Canadian Institutes of Health Research; Western Canada Research Grid; Compute Canada","keywords":"Chemistry; Electron paramagnetic resonance; Ferrocene; Pyridine; Cyclic voltammetry; Imidazole; Ligand (biochemistry); Medicinal chemistry; Thiourea; Stereochemistry; Electrochemistry; Organic chemistry; Physical chemistry; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001401961,0.0001974829,0.0003124504,0.00001548159,0.00005554912,0.000009724945,0.0003732291,0.0001582715,0.0006429279],"category_scores_gemma":[0.0002014468,0.0001812801,0.00007621591,0.0005743501,0.0002033945,0.00008450987,0.0001085258,0.0002424638,0.000003060029],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001712105,"about_ca_system_score_gemma":0.0001967307,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009441941,"about_ca_topic_score_gemma":0.000008719377,"domain_scores_codex":[0.998556,0.00001404308,0.000585781,0.0003043718,0.0003510414,0.0001888093],"domain_scores_gemma":[0.9987327,0.00004792514,0.0004169698,0.0004891876,0.0002275155,0.00008564584],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002497641,0.0003022462,0.008128663,0.0003493753,0.00003015622,4.214592e-7,0.0001111534,0.0003220261,0.9884998,0.00001810052,0.002175476,0.00003765724],"study_design_scores_gemma":[0.0008985774,0.000004982974,0.003053537,0.00007551794,0.00003614311,0.0000196715,0.0005867337,0.0004433905,0.9940968,0.0002656476,0.0003568457,0.000162149],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958743,0.0001423325,0.0000905339,0.0001777612,0.00002690366,0.00006997108,0.0001774247,0.00003783,0.003402956],"genre_scores_gemma":[0.9987214,0.0000199211,0.0000452653,0.00002522168,0.0000757381,0.00001752384,0.0005567197,0.0000216166,0.0005166593],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005597055,"threshold_uncertainty_score":0.7392387,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03606266829517678,"score_gpt":0.2521954731786364,"score_spread":0.2161328048834597,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}