{"id":"W2315276711","doi":"10.1021/jo102329c","title":"Water-Soluble Substrates of the Peptidoglycan-Modifying Enzyme <i>O-</i>Acetylpeptidoglycan Esterase (Ape1) from <i>Neisseria gonorrheae</i>","year":2011,"lang":"en","type":"article","venue":"The Journal of Organic Chemistry","topic":"Carbohydrate Chemistry and Synthesis","field":"Chemistry","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph; University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Chemistry; Peptidoglycan; Esterase; Enzyme; Biochemistry; Neisseria; Microbiology; Bacteria","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005726183,0.0004742701,0.0006620838,0.00002101447,0.0002444769,0.00005944942,0.001948852,0.0003085279,0.01197718],"category_scores_gemma":[0.0001629228,0.0002734669,0.0004738892,0.0002394065,0.000363339,0.0002072772,0.0003048193,0.000942236,0.00001972392],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001509501,"about_ca_system_score_gemma":0.0002626499,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001786541,"about_ca_topic_score_gemma":0.00002478219,"domain_scores_codex":[0.9974197,0.00006607634,0.001208065,0.0002996778,0.0004508764,0.0005555937],"domain_scores_gemma":[0.996913,0.0002928059,0.001035461,0.001252846,0.0002618926,0.0002439992],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003301388,0.0001913033,0.001248072,0.0002215663,0.0002517775,0.00001747653,0.002721037,0.00001303205,0.9945449,0.000001286324,0.0003228634,0.0001365374],"study_design_scores_gemma":[0.0008368294,0.00001756526,0.00009313742,0.0003243701,0.0004050216,0.0004581909,0.002727987,0.00001962303,0.9937212,0.0002400719,0.0008213269,0.0003347156],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9891834,0.0006315999,0.00001468592,0.0002231585,0.0002462128,0.00005702291,0.00004574226,0.00003546079,0.009562759],"genre_scores_gemma":[0.9974126,0.0001835158,0.000128021,0.00006456309,0.0005749805,0.000003382626,0.00001351424,0.00007663146,0.001542745],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01195746,"threshold_uncertainty_score":0.9999717,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01877411415310262,"score_gpt":0.1969788113544396,"score_spread":0.1782046972013369,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}