{"id":"W2315485510","doi":"10.1016/j.exphem.2014.07.244","title":"Self-renewal network activated by SCL-LMO1 confer aberrant stem cell properties to immature thymocytes","year":2014,"lang":"en","type":"article","venue":"Experimental Hematology","topic":"Single-cell and spatial transcriptomics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute for Research in Immunology and Cancer","funders":"","keywords":"Biology; Stem cell; Cell biology; Reprogramming; Progenitor cell; Thymocyte; Transcription factor; Cellular differentiation; Transplantation; Cell; Genetics; Gene; T cell; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00008546039,0.0003144891,0.0003567167,0.00002748765,0.0001531599,0.00003634877,0.0002740946,0.0003302385,0.00004037327],"category_scores_gemma":[0.000004339123,0.0002700276,0.0001031257,0.0000745522,0.00008925315,0.000006300203,0.0001181638,0.0001319069,0.00004843519],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002700464,"about_ca_system_score_gemma":0.00004113319,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003865187,"about_ca_topic_score_gemma":0.00001309254,"domain_scores_codex":[0.9984502,0.0001236575,0.0002849821,0.0005159805,0.0001236207,0.0005015599],"domain_scores_gemma":[0.9993611,0.00001351128,0.00007268192,0.0003385036,0.0000457096,0.0001684751],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004853341,0.0003046454,0.0003480732,0.00003892182,0.00005943006,0.000003047476,0.0004756437,0.0000227504,0.9889805,0.0005401355,0.008636842,0.0001046947],"study_design_scores_gemma":[0.0008744771,0.000563164,0.00001028935,0.00002308924,0.00001199361,0.0000462995,0.0002932933,0.00008382473,0.9500566,0.00001080828,0.0476878,0.0003383513],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9857594,0.009628441,0.0004413516,0.0001658601,0.0006080055,0.0003829173,0.000009893769,0.00008006155,0.002924047],"genre_scores_gemma":[0.9968039,0.00003576752,0.0008749178,0.0008993515,0.0002435881,0.00007734363,0.00009191481,0.00005452462,0.0009186877],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03905096,"threshold_uncertainty_score":0.9999752,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00892994252594925,"score_gpt":0.2121255641922309,"score_spread":0.2031956216662817,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}