{"id":"W2315593632","doi":"10.1038/onc.2014.433","title":"Signaling switch of the urotensin II vasosactive peptide GPCR: prototypic chemotaxic mechanism in glioma","year":2015,"lang":"en","type":"article","venue":"Oncogene","topic":"Cardiovascular, Neuropeptides, and Oxidative Stress Research","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research; Langley Research Center; Institut National de la Santé et de la Recherche Médicale","keywords":"Urotensin-II; Focal adhesion; Biology; Cell biology; Signal transduction; Cell migration; Autocrine signalling; Integrin; G protein-coupled receptor; Glioma; Receptor; Lamellipodium; Motility; Cancer research; Cell; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008612613,0.0001751701,0.0001134848,0.0001269624,0.0002529648,0.0003280634,0.000189923,0.0003268204,0.001571944],"category_scores_gemma":[0.00008688033,0.00006757794,0.0001887955,0.0001160836,0.0001869666,0.0002993397,0.0002188962,0.0004869135,0.000301108],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004253934,"about_ca_system_score_gemma":0.0001783791,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006842826,"about_ca_topic_score_gemma":0.0007943953,"domain_scores_codex":[0.9999098,0.00001152894,0.00000281611,0.00001748794,0.00001512932,0.00004320404],"domain_scores_gemma":[0.9999739,0.000001995819,0.000004761145,0.000002375951,0.00000374546,0.00001331429],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001059131,0.00001906457,0.000360517,0.00002524041,0.000002843863,0.0002560611,0.00003782889,0.00008399344,0.9959081,0.00165278,0.0002629625,0.001284679],"study_design_scores_gemma":[0.00005389324,0.0004722096,0.04015361,0.0000272887,0.00003008042,0.002626635,0.0008738861,0.005293573,0.9343018,0.00178132,0.01435356,0.00003211506],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932415,0.001249134,0.001453579,0.0004938359,0.00006882646,0.00001548686,0.0001955466,0.0000489234,0.003233095],"genre_scores_gemma":[0.9972563,0.0005643696,0.0004429437,0.0001435687,0.00001182808,0.000009165753,0.0001700121,0.000004105481,0.001397732],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001571944,"threshold_uncertainty_score":0.005258679,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04873142969826814,"score_gpt":0.2948039074455484,"score_spread":0.2460724777472802,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}