{"id":"W2315762222","doi":"10.1038/sj.onc.1203808","title":"UVB induced cell cycle checkpoints in an early stage human melanoma line, WM35","year":2000,"lang":"en","type":"article","venue":"Oncogene","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":false,"ca_institutions":"Health Sciences Centre; Sunnybrook Health Science Centre","funders":"","keywords":"Biology; Cyclin A; Cyclin-dependent kinase 2; Cyclin B; Cyclin E; Cyclin D1; Cyclin D; Cell cycle checkpoint; Cell cycle; CDC25A; Cyclin-dependent kinase; Cyclin-dependent kinase 1; Cyclin-dependent kinase complex; Cancer research; Cyclin A2; Cell biology; Kinase; Protein kinase A; Cell; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001173015,0.0002696784,0.0002100593,0.0003933569,0.0002349138,0.0001903358,0.0002183794,0.0002691898,0.002385879],"category_scores_gemma":[0.00009668961,0.000138398,0.0002925623,0.0002336711,0.0001370134,0.0001700888,0.0001235946,0.0006403475,0.0005748341],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003017696,"about_ca_system_score_gemma":0.0001862938,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003373998,"about_ca_topic_score_gemma":0.002433287,"domain_scores_codex":[0.9999077,0.00001683987,0.000009038853,0.00001738391,0.00001700696,0.00003189003],"domain_scores_gemma":[0.9999053,0.0000291445,0.000009337351,0.00002180816,0.00001238373,0.00002197504],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001958568,0.00005889566,0.0001424905,0.00001726093,0.000003719482,0.00003545732,0.00002639544,0.00003633197,0.9987746,0.00009370018,0.00006406711,0.0005512206],"study_design_scores_gemma":[0.00002316383,0.0006321965,0.006117717,0.000004831205,0.0000137573,0.0001511792,0.00003270608,0.000517964,0.9912703,0.00004456829,0.001188399,0.000003207359],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954282,0.001089129,0.001102946,0.00006424503,0.00002314421,0.00003785143,0.0006455404,0.00006997195,0.001538934],"genre_scores_gemma":[0.9924985,0.0004899417,0.001136033,0.00004191747,0.000006995024,0.00004520682,0.001238198,0.00002348726,0.004519805],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003373998,"threshold_uncertainty_score":0.007981598,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02478721362307607,"score_gpt":0.2953478613482325,"score_spread":0.2705606477251565,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}