{"id":"W2315762222","doi":"10.1038/sj.onc.1203808","title":"UVB induced cell cycle checkpoints in an early stage human melanoma line, WM35","year":2000,"lang":"en","type":"article","venue":"Oncogene","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":false,"ca_institutions":"Health Sciences Centre; Sunnybrook Health Science Centre","funders":"","keywords":"Biology; Cyclin A; Cyclin-dependent kinase 2; Cyclin B; Cyclin E; Cyclin D1; Cyclin D; Cell cycle checkpoint; Cell cycle; CDC25A; Cyclin-dependent kinase; Cyclin-dependent kinase 1; Cyclin-dependent kinase complex; Cancer research; Cyclin A2; Cell biology; Kinase; Protein kinase A; Cell; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001806433,0.0002262843,0.0003524175,0.0001725112,0.00006299935,0.00002413326,0.0001610702,0.0002488294,0.00238118],"category_scores_gemma":[0.00001321263,0.0002370199,0.0001012404,0.0003524878,0.00003761731,0.0001020469,0.00003207465,0.0004098972,0.0005239234],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002279934,"about_ca_system_score_gemma":0.0001617563,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001161251,"about_ca_topic_score_gemma":0.0008577683,"domain_scores_codex":[0.9983598,0.00006890748,0.0003802227,0.000457521,0.00031648,0.0004170407],"domain_scores_gemma":[0.9989449,0.000009965539,0.00007450907,0.0006402495,0.00005219442,0.0002781447],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001836203,0.0005034425,0.003316368,0.00003090804,0.0000232789,0.0005882938,0.0005955627,0.00007958052,0.9785744,0.00001526914,0.00008206104,0.01600724],"study_design_scores_gemma":[0.007029071,0.002156257,0.04987334,0.0001289014,0.00008001822,0.00003763831,0.0000819155,0.0003312956,0.9336634,0.00005342039,0.006110997,0.0004537587],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9595886,0.0002271276,0.00001010718,0.0001075584,0.0000968883,0.0004245566,0.00002239864,0.0001023016,0.03942047],"genre_scores_gemma":[0.9923107,0.00003555782,0.0004124745,0.0003316961,0.0002226923,0.0000289072,0.00008635959,0.00007817172,0.006493435],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04655698,"threshold_uncertainty_score":0.9985308,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02478721362307607,"score_gpt":0.2953478613482325,"score_spread":0.2705606477251565,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}