{"id":"W2315806036","doi":"10.1158/1538-7445.am2011-2996","title":"Abstract 2996: DNA-damaging agents disrupt telomere structure","year":2011,"lang":"en","type":"article","venue":"Cancer Research","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Cégep de Sherbrooke; Université de Sherbrooke","funders":"","keywords":"Telomere; Shelterin; Telomerase; Telomere-binding protein; DNA; Biology; DNA repair; Molecular biology; DNA damage; Gene; Cell biology; Genetics; DNA-binding protein; Transcription factor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009819281,0.0003743533,0.0003247902,0.000195198,0.0001184446,0.0001751746,0.0001806412,0.0003475656,0.003637137],"category_scores_gemma":[0.0001139715,0.0001394245,0.0002168893,0.0001728459,0.0001114553,0.0001452711,0.0001521276,0.0004239155,0.0008059503],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001667113,"about_ca_system_score_gemma":0.0001083209,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000279072,"about_ca_topic_score_gemma":0.0002537453,"domain_scores_codex":[0.9998838,0.0000164283,0.00001469811,0.00002441717,0.00003993842,0.00002079496],"domain_scores_gemma":[0.9999129,0.00001923107,0.00002841002,0.00001108082,0.00001004536,0.00001846776],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00006821375,0.00001587938,0.00005473126,0.00003950681,0.000002768496,0.00003188424,0.00000273145,0.00001950022,0.999175,0.00001395924,0.00004982173,0.0005259134],"study_design_scores_gemma":[0.00001010625,0.0003288274,0.00209069,0.000005886451,0.000008819688,0.0002932737,0.000006622823,0.000181545,0.9953673,0.00001431366,0.001690956,0.00000180936],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9876036,0.004899809,0.003000153,0.0001441995,0.0001272098,0.00005577491,0.001993987,0.0001875803,0.001987607],"genre_scores_gemma":[0.9839762,0.002091947,0.003177541,0.0001135399,0.00002884174,0.00005132175,0.002841572,0.00004669245,0.007672358],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003637137,"threshold_uncertainty_score":0.01216745,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1835115424267239,"score_gpt":0.4284177526737415,"score_spread":0.2449062102470176,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}