{"id":"W2315892755","doi":"10.1158/1538-7445.am2013-lb-266","title":"Abstract LB-266: SIRT1 governs GnRH neuron migration and The Kallmann syndrome phenotype.","year":2013,"lang":"en","type":"article","venue":"Cancer Research","topic":"Ovarian function and disorders","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Endocrinology; Internal medicine; Biology; Forebrain; Sirtuin 1; Hypothalamus; Kallmann syndrome; Anterior pituitary; Cell biology; Medicine; Central nervous system; Downregulation and upregulation; Hormone; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001127378,0.0005229631,0.0002192582,0.0005828861,0.0003185773,0.0002691908,0.0004077579,0.000621506,0.007220906],"category_scores_gemma":[0.0001361973,0.0002305322,0.0003407643,0.0002612623,0.000543028,0.0001349297,0.0002831384,0.0008528263,0.001483419],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003217389,"about_ca_system_score_gemma":0.0001994813,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008781207,"about_ca_topic_score_gemma":0.001905773,"domain_scores_codex":[0.9998237,0.0000212999,0.00002503672,0.0000547124,0.0000499901,0.00002533955],"domain_scores_gemma":[0.9998129,0.00002155938,0.000078277,0.00001364167,0.000008165048,0.00006535556],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001458991,0.00002841442,0.0004472032,0.0000410388,0.000009416376,0.0008030144,0.00002002941,0.00004994377,0.9968263,0.0001865909,0.0002322004,0.001209981],"study_design_scores_gemma":[0.0001786617,0.0006596751,0.04104338,0.00004310628,0.00009662934,0.01193011,0.0001540049,0.001430633,0.928573,0.0003535252,0.01549767,0.00003963445],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9852065,0.001402623,0.003605203,0.0005908522,0.0002461226,0.00006208607,0.003933994,0.0004903781,0.004462118],"genre_scores_gemma":[0.9846,0.0007524937,0.002274974,0.0002058058,0.00004456719,0.00004904178,0.002036958,0.0001331257,0.009902891],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007220906,"threshold_uncertainty_score":0.02415627,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05047868861271645,"score_gpt":0.3475225003780825,"score_spread":0.297043811765366,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}