{"id":"W2315916150","doi":"10.1097/00001813-200209000-00013","title":"Antineoplastic action of 5-aza-2′-deoxycytidine and phenylbutyrate on human lung carcinoma cells","year":2002,"lang":"en","type":"article","venue":"Anti-Cancer Drugs","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":69,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"","keywords":"Cancer research; Clonogenic assay; Histone deacetylase; Acetylation; Phenylbutyrate; Histone; Carcinogenesis; DNA methylation; Chemistry; Trichostatin A; Gene silencing; Lung cancer; Biology; Molecular biology; DNA; Cell; Gene expression; Biochemistry; Gene; Medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008402357,0.0001456472,0.0001628691,0.0000553941,0.00008724378,0.00001523675,0.00007573807,0.0001029893,0.00005027295],"category_scores_gemma":[0.000009901881,0.000142434,0.00005353108,0.00007878432,0.00006297581,0.000005071371,0.00004177423,0.00006966865,0.000005185945],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001082358,"about_ca_system_score_gemma":0.0000121378,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007807142,"about_ca_topic_score_gemma":0.00001867779,"domain_scores_codex":[0.9991608,0.0000363794,0.0002024039,0.0002998568,0.000121366,0.0001791425],"domain_scores_gemma":[0.9995154,0.00001405006,0.0001319561,0.0002162302,0.00006639052,0.0000559989],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001638398,0.0001261794,0.01109238,0.00005417317,0.00002667789,6.491088e-7,0.00008502647,0.00009463033,0.985669,0.00003349964,0.0004040067,0.00239746],"study_design_scores_gemma":[0.001053304,0.0001887721,0.01146078,0.00002282509,0.00003052456,4.616214e-7,0.00002924648,0.0008822,0.9840984,0.00001718665,0.002055374,0.0001609107],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961061,0.002261971,0.0001614137,0.0000687504,0.0001845614,0.0001180878,0.00002717645,0.0000081195,0.001063758],"genre_scores_gemma":[0.9958898,0.002799168,0.00006203102,0.00005390648,0.0002314421,0.000008799998,0.00002971532,0.00002197416,0.0009031366],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002236549,"threshold_uncertainty_score":0.5808289,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03047106055752515,"score_gpt":0.2963949783436929,"score_spread":0.2659239177861678,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}